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==Crytsal structure of human Pleiotropic Regulator 1 (PRL1)==
==Crytsal structure of human Pleiotropic Regulator 1 (PRL1)==
<StructureSection load='4yvd' size='340' side='right' caption='[[4yvd]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='4yvd' size='340' side='right'caption='[[4yvd]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4yvd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YVD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YVD FirstGlance]. <br>
<table><tr><td colspan='2'>[[4yvd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YVD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YVD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yvd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4yvd RCSB], [http://www.ebi.ac.uk/pdbsum/4yvd PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yvd OCA], [https://pdbe.org/4yvd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yvd RCSB], [https://www.ebi.ac.uk/pdbsum/4yvd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yvd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PLRG1_HUMAN PLRG1_HUMAN]] Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.  
[https://www.uniprot.org/uniprot/PLRG1_HUMAN PLRG1_HUMAN] Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Homo sapiens]]
[[Category: Bountra, C]]
[[Category: Large Structures]]
[[Category: Brown, P J]]
[[Category: Arrowsmith CH]]
[[Category: Dong, A]]
[[Category: Bountra C]]
[[Category: Edwards, A M]]
[[Category: Brown PJ]]
[[Category: He, H]]
[[Category: Dong A]]
[[Category: Li, Y]]
[[Category: Edwards AM]]
[[Category: Min, J]]
[[Category: He H]]
[[Category: Structural genomic]]
[[Category: Li Y]]
[[Category: Tempel, W]]
[[Category: Min J]]
[[Category: Wu, H]]
[[Category: Tempel W]]
[[Category: Xu, C]]
[[Category: Wu H]]
[[Category: Zeng, H]]
[[Category: Xu C]]
[[Category: Mrna processing]]
[[Category: Zeng H]]
[[Category: Mrna splicing]]
[[Category: Rna binding protein]]
[[Category: Sgc]]
[[Category: Wd40 repeat]]

Latest revision as of 08:08, 27 September 2023

Crytsal structure of human Pleiotropic Regulator 1 (PRL1)

4yvd, resolution 1.70Å

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