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[[Image:2yvu.gif|left|200px]]


{{Structure
==Crystal structure of APE1195==
|PDB= 2yvu |SIZE=350|CAPTION= <scene name='initialview01'>2yvu</scene>, resolution 2.10&Aring;
<StructureSection load='2yvu' size='340' side='right'caption='[[2yvu]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2yvu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix_K1 Aeropyrum pernix K1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YVU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YVU FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenylyl-sulfate_kinase Adenylyl-sulfate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.25 2.7.1.25]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
|GENE= cysC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=56636 Aeropyrum pernix])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yvu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yvu OCA], [https://pdbe.org/2yvu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yvu RCSB], [https://www.ebi.ac.uk/pdbsum/2yvu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yvu ProSAT], [https://www.topsan.org/Proteins/RSGI/2yvu TOPSAN]</span></td></tr>
}}
</table>
 
== Function ==
'''Crystal structure of APE1195'''
[https://www.uniprot.org/uniprot/CYSC_AERPE CYSC_AERPE] Catalyzes the synthesis of activated sulfate.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
2YVU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YVU OCA].  
  <jmolCheckbox>
[[Category: Adenylyl-sulfate kinase]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yv/2yvu_consurf.spt"</scriptWhenChecked>
[[Category: Aeropyrum pernix]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Single protein]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Bessho, Y.]]
  </jmolCheckbox>
[[Category: Ishii, R.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yvu ConSurf].
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
<div style="clear:both"></div>
[[Category: Yokoyama, S.]]
__TOC__
[[Category: kinase]]
</StructureSection>
[[Category: national project on protein structural and functional analyse]]
[[Category: Aeropyrum pernix K1]]
[[Category: nppsfa]]
[[Category: Large Structures]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: Bessho Y]]
[[Category: rsgi]]
[[Category: Ishii R]]
[[Category: structural genomic]]
[[Category: Yokoyama S]]
[[Category: transferase]]
 
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