Sandbox Reserved 1: Difference between revisions
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{{Template:Sandbox Reserved Eric Martz}} | {{Template:Sandbox Reserved Eric Martz}} | ||
<!-- INSERT YOUR SCENES AND TEXT BELOW THIS LINE --> | <!-- INSERT YOUR SCENES AND TEXT BELOW THIS LINE --> | ||
== 4HJE: CRYSTAL STRUCTURE OF P53 CORE DOMAIN IN COMPLEX WITH DNA == | |||
<Structure load='4hje' size='520' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | |||
<font size="+2"> | |||
This protein ('''celluler tumor antigen p53''') is known as a tumor suppressor. | |||
So, this protein contact DNA. | |||
The regions contacting DNA are | |||
<scene name='54/545858/Scene1/1'>positively charged</scene>. | |||
<scene name='54/545858/Binding/2'>Lys 120, Arg 248, Arg 280</scene> are important for sequence-specific binding. | |||
Lys 120, Arg 280 contact major groove, and Arg 248 contacts minor groove. | |||
</font> | |||
