2z15: Difference between revisions

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[[Image:2z15.jpg|left|200px]]


{{Structure
==Crystal structure of human Tob1 protein==
|PDB= 2z15 |SIZE=350|CAPTION= <scene name='initialview01'>2z15</scene>, resolution 2.30&Aring;
<StructureSection load='2z15' size='340' side='right'caption='[[2z15]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2z15]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z15 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
|GENE= TOB1, TOB, TROB1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z15 OCA], [https://pdbe.org/2z15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z15 RCSB], [https://www.ebi.ac.uk/pdbsum/2z15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z15 ProSAT], [https://www.topsan.org/Proteins/RSGI/2z15 TOPSAN]</span></td></tr>
}}
</table>
 
== Function ==
'''Crystal structure of human Tob1 protein'''
[https://www.uniprot.org/uniprot/TOB1_HUMAN TOB1_HUMAN] Anti-proliferative protein that interacts with the erbB-2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
2Z15 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z15 OCA].  
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z1/2z15_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z15 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Kishishita, S.]]
[[Category: Kishishita S]]
[[Category: Murayama, K.]]
[[Category: Murayama K]]
[[Category: Nishino, A.]]
[[Category: Nishino A]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Saito K]]
[[Category: Saito, K.]]
[[Category: Shirouzu M]]
[[Category: Shirouzu, M.]]
[[Category: Terada T]]
[[Category: Terada, T.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: human tob1 protein]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: phosphorylation]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: signaling protein]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:50:59 2008''

Latest revision as of 13:55, 13 March 2024

Crystal structure of human Tob1 protein

2z15, resolution 2.30Å

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