2z5g: Difference between revisions

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[[Image:2z5g.gif|left|200px]]


{{Structure
==Crystal structure of T1 lipase F16L mutant==
|PDB= 2z5g |SIZE=350|CAPTION= <scene name='initialview01'>2z5g</scene>, resolution 1.80&Aring;
<StructureSection load='2z5g' size='340' side='right'caption='[[2z5g]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=CL:CHLORIDE ION'>CL</scene>
<table><tr><td colspan='2'>[[2z5g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_zalihae Geobacillus zalihae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z5G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z5G FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Triacylglycerol_lipase Triacylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z5g OCA], [https://pdbe.org/2z5g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z5g RCSB], [https://www.ebi.ac.uk/pdbsum/2z5g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z5g ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q842J9_9BACI Q842J9_9BACI]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z5/2z5g_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z5g ConSurf].
<div style="clear:both"></div>


'''Crystal structure of T1 lipase F16L mutant'''
==See Also==
 
*[[Lipase 3D Structures|Lipase 3D Structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2Z5G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_zalihae Geobacillus zalihae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z5G OCA].
 
==Reference==
Novel cation-pi interaction revealed by crystal structure of thermoalkalophilic lipase., Matsumura H, Yamamoto T, Leow TC, Mori T, Salleh AB, Basri M, Inoue T, Kai Y, Rahman RN, Proteins. 2008 Feb 1;70(2):592-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17932933 17932933]
[[Category: Geobacillus zalihae]]
[[Category: Geobacillus zalihae]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Triacylglycerol lipase]]
[[Category: Inoue T]]
[[Category: Inoue, T.]]
[[Category: Kai Y]]
[[Category: Kai, Y.]]
[[Category: Matsumura H]]
[[Category: Matsumura, H.]]
[[Category: Yamamoto T]]
[[Category: Yamamoto, T.]]
[[Category: CA]]
[[Category: CL]]
[[Category: ZN]]
[[Category: cation-pi interaction]]
[[Category: hydrolase]]
[[Category: lipase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:52:19 2008''

Latest revision as of 13:22, 1 November 2023

Crystal structure of T1 lipase F16L mutant

2z5g, resolution 1.80Å

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