Sandbox Reserved 1: Difference between revisions
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== 4HJE: CRYSTAL STRUCTURE OF P53 CORE DOMAIN IN COMPLEX WITH DNA == | == 4HJE: CRYSTAL STRUCTURE OF P53 CORE DOMAIN IN COMPLEX WITH DNA == | ||
<Structure load='4hje' size=' | <Structure load='4hje' size='520' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | ||
<font size="+2"> | |||
This protein ('''celluler tumor antigen p53''') is known as a tumor suppressor. | This protein ('''celluler tumor antigen p53''') is known as a tumor suppressor. | ||
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The regions contacting DNA are | The regions contacting DNA are | ||
<scene name='54/545858/Scene1/1'>positively charged</scene>. | <scene name='54/545858/Scene1/1'>positively charged</scene>. | ||
<scene name='54/545858/Binding/2'>Lys 120, Arg 248, Arg 280</scene> are important for sequence-specific binding. | |||
Lys 120, Arg 280 contact major groove, and Arg 248 contacts minor groove. | |||
</font> | |||
