2z84: Difference between revisions

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[[Image:2z84.jpg|left|200px]]


{{Structure
==Insights from crystal and solution structures of mouse UfSP1==
|PDB= 2z84 |SIZE=350|CAPTION= <scene name='initialview01'>2z84</scene>, resolution 1.7&Aring;
<StructureSection load='2z84' size='340' side='right'caption='[[2z84]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
|SITE=
== Structural highlights ==
|LIGAND=
<table><tr><td colspan='2'>[[2z84]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z84 FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z84 OCA], [https://pdbe.org/2z84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z84 RCSB], [https://www.ebi.ac.uk/pdbsum/2z84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z84 ProSAT]</span></td></tr>
}}
</table>
 
== Function ==
'''Insights from crystal and solution structures of mouse UfSP1'''
[https://www.uniprot.org/uniprot/UFSP1_MOUSE UFSP1_MOUSE] Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, an ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins.<ref>PMID:17182609</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
2Z84 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z84 OCA].  
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z8/2z84_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z84 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Ahn HC]]
[[Category: Ahn, H C.]]
[[Category: Chung CH]]
[[Category: Chung, C H.]]
[[Category: Ha BH]]
[[Category: Ha, B H.]]
[[Category: Kang SH]]
[[Category: Kang, S H.]]
[[Category: Kim EE]]
[[Category: Kim, E E.]]
[[Category: Tanaka K]]
[[Category: Tanaka, K.]]
[[Category: alpha/beta]]
[[Category: hydrolase]]
[[Category: papain like fold]]
[[Category: protease]]
[[Category: thiol protease]]
[[Category: ubl conjugation pathway]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:52:46 2008''