2n3a: Difference between revisions

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'''Unreleased structure'''


The entry 2n3a is ON HOLD
==Solution structure of LEDGF/p75 IBD in complex with POGZ peptide (1389-1404)==
 
<StructureSection load='2n3a' size='340' side='right'caption='[[2n3a]]' scene=''>
Authors: Tesina, P., Cermakova, K., Horejsi, M., Prochazkova, K., Fabry, M., Sharma, S., Christ, F., Demeulemeester, J., Debyser, Z., De Rijck, J., Veverka, V., Rezacova, P.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2n3a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N3A FirstGlance]. <br>
Description: Solution structure of LEDGF/p75 IBD in complex with POGZ peptide (1389-1404)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n3a OCA], [https://pdbe.org/2n3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n3a RCSB], [https://www.ebi.ac.uk/pdbsum/2n3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n3a ProSAT]</span></td></tr>
[[Category: De Rijck, J]]
</table>
[[Category: Fabry, M]]
== Function ==
[[Category: Veverka, V]]
[https://www.uniprot.org/uniprot/POGZ_HUMAN POGZ_HUMAN] Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms.<ref>PMID:20562864</ref>
[[Category: Cermakova, K]]
== References ==
[[Category: Debyser, Z]]
<references/>
[[Category: Demeulemeester, J]]
__TOC__
[[Category: Christ, F]]
</StructureSection>
[[Category: Sharma, S]]
[[Category: Homo sapiens]]
[[Category: Rezacova, P]]
[[Category: Large Structures]]
[[Category: Horejsi, M]]
[[Category: Cermakova K]]
[[Category: Prochazkova, K]]
[[Category: Christ F]]
[[Category: Tesina, P]]
[[Category: De Rijck J]]
[[Category: Debyser Z]]
[[Category: Demeulemeester J]]
[[Category: Fabry M]]
[[Category: Horejsi M]]
[[Category: Prochazkova K]]
[[Category: Rezacova P]]
[[Category: Sharma S]]
[[Category: Tesina P]]
[[Category: Veverka V]]
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