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==The Crystal Structure of the Pyocin S2 Nuclease Domain, Immunity Protein Complex at 1.8 Angstroms==
==The Crystal Structure of the Pyocin S2 Nuclease Domain, Immunity Protein Complex at 1.8 Angstroms==
<StructureSection load='4qko' size='340' side='right' caption='[[4qko]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4qko' size='340' side='right'caption='[[4qko]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4qko]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QKO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QKO FirstGlance]. <br>
<table><tr><td colspan='2'>[[4qko]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QKO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QKO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3u43|3u43]], [[7cei|7cei]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qko OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qko RCSB], [http://www.ebi.ac.uk/pdbsum/4qko PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qko OCA], [https://pdbe.org/4qko PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qko RCSB], [https://www.ebi.ac.uk/pdbsum/4qko PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qko ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PYS2_PSEAE PYS2_PSEAE]] Causes breakdown of chromosomal DNA as well as complete inhibition of lipid synthesis in sensitive cells.
[https://www.uniprot.org/uniprot/IMM2_PSEAE IMM2_PSEAE]  
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cogdell, C J]]
[[Category: Large Structures]]
[[Category: Grinter, R]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Josts, I]]
[[Category: Cogdell CJ]]
[[Category: Roszak, A W]]
[[Category: Grinter R]]
[[Category: Walker, D]]
[[Category: Josts I]]
[[Category: Antimicrobial protein]]
[[Category: Roszak AW]]
[[Category: Bacterial cytotoxin]]
[[Category: Walker D]]
[[Category: Bacteriocin]]
[[Category: Colicin nuclease immunity protein complex]]
[[Category: Hnh nuclease domain]]

Latest revision as of 15:07, 8 November 2023

The Crystal Structure of the Pyocin S2 Nuclease Domain, Immunity Protein Complex at 1.8 Angstroms

4qko, resolution 1.80Å

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