3bo7: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
(13 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:3bo7.jpg|left|200px]]


{{Structure
==Crystal structure of Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, 541.m00136==
|PDB= 3bo7 |SIZE=350|CAPTION= <scene name='initialview01'>3bo7</scene>, resolution 2.350&Aring;
<StructureSection load='3bo7' size='340' side='right'caption='[[3bo7]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+202'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+B+202'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+D+202'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+B+203'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+D+203'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+C+202'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Residue+D+204'>AC7</scene>, <scene name='pdbsite=AC8:So4+Binding+Site+For+Residue+B+204'>AC8</scene>, <scene name='pdbsite=AC9:So4+Binding+Site+For+Residue+C+203'>AC9</scene>, <scene name='pdbsite=BC1:So4+Binding+Site+For+Residue+C+204'>BC1</scene>, <scene name='pdbsite=BC2:So4+Binding+Site+For+Residue+B+205'>BC2</scene>, <scene name='pdbsite=BC3:So4+Binding+Site+For+Residue+D+205'>BC3</scene>, <scene name='pdbsite=BC4:So4+Binding+Site+For+Residue+A+203'>BC4</scene>, <scene name='pdbsite=BC5:So4+Binding+Site+For+Residue+A+204'>BC5</scene>, <scene name='pdbsite=BC6:So4+Binding+Site+For+Residue+C+205'>BC6</scene>, <scene name='pdbsite=BC7:So4+Binding+Site+For+Residue+D+206'>BC7</scene>, <scene name='pdbsite=BC8:So4+Binding+Site+For+Residue+A+205'>BC8</scene>, <scene name='pdbsite=BC9:So4+Binding+Site+For+Residue+C+206'>BC9</scene>, <scene name='pdbsite=CC1:So4+Binding+Site+For+Residue+C+207'>CC1</scene>, <scene name='pdbsite=CC2:So4+Binding+Site+For+Residue+A+206'>CC2</scene>, <scene name='pdbsite=CC3:So4+Binding+Site+For+Residue+C+208'>CC3</scene>, <scene name='pdbsite=CC4:Edo+Binding+Site+For+Residue+A+207'>CC4</scene>, <scene name='pdbsite=CC5:Edo+Binding+Site+For+Residue+D+210'>CC5</scene>, <scene name='pdbsite=CC6:Edo+Binding+Site+For+Residue+D+211'>CC6</scene>, <scene name='pdbsite=CC7:Edo+Binding+Site+For+Residue+C+209'>CC7</scene> and <scene name='pdbsite=CC8:Edo+Binding+Site+For+Residue+G+12'>CC8</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
<table><tr><td colspan='2'>[[3bo7]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Tolypocladium_inflatum Tolypocladium inflatum] and [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BO7 FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
|GENE= 541.m00136 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 Toxoplasma gondii])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo7 OCA], [https://pdbe.org/3bo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bo7 RCSB], [https://www.ebi.ac.uk/pdbsum/3bo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bo7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/D0VWS5_TOXGO D0VWS5_TOXGO] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).[RuleBase:RU004223]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bo/3bo7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bo7 ConSurf].
<div style="clear:both"></div>


'''Crystal structure of Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, 541.m00136'''
==See Also==
 
*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3BO7 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO7 OCA].
[[Category: Large Structures]]
[[Category: Protein complex]]
[[Category: Tolypocladium inflatum]]
[[Category: Toxoplasma gondii]]
[[Category: Toxoplasma gondii]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Artz, J D.]]
[[Category: Artz JD]]
[[Category: Bochkarev, A.]]
[[Category: Bochkarev A]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Hui, R.]]
[[Category: Hui R]]
[[Category: Khuu, C.]]
[[Category: Khuu C]]
[[Category: Kozieradzki, I.]]
[[Category: Kozieradzki I]]
[[Category: Lew, J.]]
[[Category: Lew J]]
[[Category: Lin, Y H.]]
[[Category: Lin YH]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Schapira M]]
[[Category: Schapira, M.]]
[[Category: Sun X]]
[[Category: Sun, X.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Wernimont AK]]
[[Category: Wernimont, A K.]]
[[Category: Xiao T]]
[[Category: Xiao, T.]]
[[Category: Zhao Y]]
[[Category: Zhao, Y.]]
[[Category: EDO]]
[[Category: SO4]]
[[Category: cyclosporin some]]
[[Category: isomerase]]
[[Category: large cyclophilin]]
[[Category: sgc]]
[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: toxoplasma gondii]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:00:14 2008''
Retrieved from "https://proteopedia.org/3bo7"