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[[Image:3c9f.jpg|left|200px]]


{{Structure
==Crystal structure of 5'-nucleotidase from Candida albicans SC5314==
|PDB= 3c9f |SIZE=350|CAPTION= <scene name='initialview01'>3c9f</scene>, resolution 1.90&Aring;
<StructureSection load='3c9f' size='340' side='right'caption='[[3c9f]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+601'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+B+601'>AC2</scene>, <scene name='pdbsite=AC3:Na+Binding+Site+For+Residue+B+603'>AC3</scene>, <scene name='pdbsite=AC4:Na+Binding+Site+For+Residue+B+604'>AC4</scene>, <scene name='pdbsite=AC5:Na+Binding+Site+For+Residue+A+605'>AC5</scene>, <scene name='pdbsite=AC6:Na+Binding+Site+For+Residue+B+606'>AC6</scene>, <scene name='pdbsite=AC7:Fmt+Binding+Site+For+Residue+B+607'>AC7</scene> and <scene name='pdbsite=AC8:Fmt+Binding+Site+For+Residue+A+607'>AC8</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=FMT:FORMIC ACID'>FMT</scene>
<table><tr><td colspan='2'>[[3c9f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C9F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C9F FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
|GENE= USHA, CaO19.12802, CaO19.5342 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237561 Candida albicans SC5314])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c9f OCA], [https://pdbe.org/3c9f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c9f RCSB], [https://www.ebi.ac.uk/pdbsum/3c9f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c9f ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3c9f TOPSAN]</span></td></tr>
 
</table>
'''Crystal structure of 5'-nucleotidase from Candida albicans SC5314'''
== Function ==
 
[https://www.uniprot.org/uniprot/Q5A5Q7_CANAL Q5A5Q7_CANAL]  
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
3C9F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Candida_albicans_sc5314 Candida albicans sc5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C9F OCA].
Check<jmol>
[[Category: Candida albicans sc5314]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/3c9f_consurf.spt"</scriptWhenChecked>
[[Category: Almo, S C.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Bain, K.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Burley, S K.]]
  </jmolCheckbox>
[[Category: Eberle, M.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c9f ConSurf].
[[Category: Gilmore, M.]]
<div style="clear:both"></div>
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
__TOC__
[[Category: Patskovsky, Y.]]
</StructureSection>
[[Category: Romero, R.]]
[[Category: Candida albicans SC5314]]
[[Category: Sauder, J M.]]
[[Category: Large Structures]]
[[Category: Smith, D.]]
[[Category: Almo SC]]
[[Category: Wasserman, S R.]]
[[Category: Bain K]]
[[Category: FMT]]
[[Category: Burley SK]]
[[Category: NA]]
[[Category: Eberle M]]
[[Category: ZN]]
[[Category: Gilmore M]]
[[Category: 2s']]
[[Category: Patskovsky Y]]
[[Category: 3'-cyclic phosphodiesterase]]
[[Category: Romero R]]
[[Category: 5'-nucleotidase]]
[[Category: Sauder JM]]
[[Category: hydrolase]]
[[Category: Smith D]]
[[Category: new york structural genomix research consortium]]
[[Category: Wasserman SR]]
[[Category: nysgxrc]]
[[Category: protein structure initiative]]
[[Category: psi-2]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:03:07 2008''

Latest revision as of 09:33, 21 February 2024

Crystal structure of 5'-nucleotidase from Candida albicans SC5314

3c9f, resolution 1.90Å

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