5bym: Difference between revisions
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==Crystal structure of the RNA-binding domain of yeast Puf5p bound to SMX2 RNA== | |||
<StructureSection load='5bym' size='340' side='right'caption='[[5bym]], [[Resolution|resolution]] 2.71Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5bym]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BYM FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.708Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bym OCA], [https://pdbe.org/5bym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bym RCSB], [https://www.ebi.ac.uk/pdbsum/5bym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bym ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Hall | == Function == | ||
[https://www.uniprot.org/uniprot/MPT5_YEAST MPT5_YEAST] RNA-binding protein involved in post-transcriptional regulation. Negatively regulates expression of HO by binding to the 3'-UTR of HO mRNA. Predominantly binds to mRNAs encoding chromatin modifiers and spindle pole body components. Recognizes and binds to 5'-TGTAA[CT]A[AT]TA-3' in the 3'-UTR of target mRNAs. Multicopy suppressor of POP2 mutation. Required for high temperature growth.<ref>PMID:11157761</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Hall TMT]] | |||
[[Category: Qiu C]] | |||
Latest revision as of 12:18, 6 March 2024
Crystal structure of the RNA-binding domain of yeast Puf5p bound to SMX2 RNA
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