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[[Image:3cb3.jpg|left|200px]]


{{Structure
==Crystal structure of L-Talarate dehydratase from Polaromonas sp. JS666 complexed with Mg and L-glucarate==
|PDB= 3cb3 |SIZE=350|CAPTION= <scene name='initialview01'>3cb3</scene>, resolution 2.00&Aring;
<StructureSection load='3cb3' size='340' side='right'caption='[[3cb3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Mg+Binding+Site+For+Residue+A+501'>AC1</scene>, <scene name='pdbsite=AC2:Mg+Binding+Site+For+Residue+B+502'>AC2</scene>, <scene name='pdbsite=AC3:Mg+Binding+Site+For+Residue+C+501'>AC3</scene>, <scene name='pdbsite=AC4:Mg+Binding+Site+For+Residue+D+502'>AC4</scene>, <scene name='pdbsite=AC5:Mg+Binding+Site+For+Residue+A+502'>AC5</scene>, <scene name='pdbsite=AC6:Mg+Binding+Site+For+Residue+B+503'>AC6</scene>, <scene name='pdbsite=AC7:Mg+Binding+Site+For+Residue+C+502'>AC7</scene>, <scene name='pdbsite=AC8:Mg+Binding+Site+For+Residue+D+503'>AC8</scene>, <scene name='pdbsite=AC9:Lgt+Binding+Site+For+Residue+A+601'>AC9</scene>, <scene name='pdbsite=BC1:Lgt+Binding+Site+For+Residue+B+601'>BC1</scene>, <scene name='pdbsite=BC2:Lgt+Binding+Site+For+Residue+C+601'>BC2</scene> and <scene name='pdbsite=BC3:Lgt+Binding+Site+For+Residue+D+601'>BC3</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=LGT:L-GLUCARIC ACID'>LGT</scene>
<table><tr><td colspan='2'>[[3cb3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Polaromonas_sp._JS666 Polaromonas sp. JS666]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CB3 FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE= Bpro_0435 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=296591 Polaromonas sp. JS666])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LGT:L-GLUCARIC+ACID'>LGT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cb3 OCA], [https://pdbe.org/3cb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cb3 RCSB], [https://www.ebi.ac.uk/pdbsum/3cb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cb3 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3cb3 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q12GE3_POLSJ Q12GE3_POLSJ]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cb/3cb3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cb3 ConSurf].
<div style="clear:both"></div>


'''Crystal structure of L-Talarate dehydratase from Polaromonas sp. JS666 complexed with Mg and L-glucarate'''
==See Also==
 
*[[Mandelate racemase/muconate lactonizing enzyme 3D structures|Mandelate racemase/muconate lactonizing enzyme 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3CB3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Polaromonas_sp._js666 Polaromonas sp. js666]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CB3 OCA].
[[Category: Large Structures]]
[[Category: Polaromonas sp. js666]]
[[Category: Polaromonas sp. JS666]]
[[Category: Single protein]]
[[Category: Almo SC]]
[[Category: Almo, S C.]]
[[Category: Burley SK]]
[[Category: Burley, S K.]]
[[Category: Fedorov AA]]
[[Category: Fedorov, A A.]]
[[Category: Fedorov EV]]
[[Category: Fedorov, E V.]]
[[Category: Gerlt JA]]
[[Category: Gerlt, J A.]]
[[Category: Yew WS]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Yew, W S.]]
[[Category: LGT]]
[[Category: MG]]
[[Category: isomerase]]
[[Category: l-glucarate]]
[[Category: l-talarate dehydratase]]
[[Category: new york structural genomix research consortium]]
[[Category: nysgxrc]]
[[Category: protein structure initiative]]
[[Category: psi-2]]
[[Category: structural genomic]]
[[Category: target 9382a]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:03:21 2008''

Latest revision as of 09:34, 21 February 2024

Crystal structure of L-Talarate dehydratase from Polaromonas sp. JS666 complexed with Mg and L-glucarate

3cb3, resolution 2.00Å

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