5c3i: Difference between revisions

(6 intermediate revisions by the same user not shown)

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5c3i is ~~ON HOLD~~

==Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2==

== Structural highlights ==

<table><tr><td colspan='2'>[[5c3i]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C3I FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c3i OCA], [https://pdbe.org/5c3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c3i RCSB], [https://www.ebi.ac.uk/pdbsum/5c3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c3i ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/ASF1A_HUMAN ASF1A_HUMAN] Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.<ref>PMID:10759893</ref> <ref>PMID:11897662</ref> <ref>PMID:12842904</ref> <ref>PMID:14718166</ref> <ref>PMID:15621527</ref> <ref>PMID:16151251</ref> <ref>PMID:15664198</ref>

~~Authors: Wang, H., Wang, M., Yang, N., Xu, R.M.~~

==See Also==

*[[Anti-silencing factor 3D structures|Anti-silencing factor 3D structures]]

~~Description~~: ~~Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2~~

== References ==

[[Category: ~~Unreleased~~ Structures]]

[[Category: Wang~~, M~~]]

__TOC__

[[Category: ~~Xu, R.~~M]]

</StructureSection>

[[Category: ~~Yang, N~~]]

[[Category: Homo sapiens]]

[[Category: ~~Wang, H~~]]

[[Category: Large Structures]]

[[Category: Wang H]]

[[Category: Wang M]]

[[Category: Xu RM]]

[[Category: Yang N]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5c3i is ON HOLD
+==Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2==
+<StructureSection load='5c3i' size='340' side='right'caption='[[5c3i]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5c3i]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C3I FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c3i OCA], [https://pdbe.org/5c3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c3i RCSB], [https://www.ebi.ac.uk/pdbsum/5c3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c3i ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ASF1A_HUMAN ASF1A_HUMAN] Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.<ref>PMID:10759893</ref> <ref>PMID:11897662</ref> <ref>PMID:12842904</ref> <ref>PMID:14718166</ref> <ref>PMID:15621527</ref> <ref>PMID:16151251</ref> <ref>PMID:15664198</ref>
-Authors: Wang, H., Wang, M., Yang, N., Xu, R.M.
+==See Also==
+*[[Anti-silencing factor 3D structures|Anti-silencing factor 3D structures]]
-Description: Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Wang, M]]
+__TOC__
-[[Category: Xu, R.M]]
+</StructureSection>
-[[Category: Yang, N]]
+[[Category: Homo sapiens]]
-[[Category: Wang, H]]
+[[Category: Large Structures]]
+[[Category: Wang H]]
+[[Category: Wang M]]
+[[Category: Xu RM]]
+[[Category: Yang N]]