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==Crystal structure of scFv-SM3 in complex with APD-SGalNAc-RP==
==Crystal structure of scFv-SM3 in complex with APD-SGalNAc-RP==
<StructureSection load='5a2i' size='340' side='right' caption='[[5a2i]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
<StructureSection load='5a2i' size='340' side='right'caption='[[5a2i]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5a2i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A2I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A2I FirstGlance]. <br>
<table><tr><td colspan='2'>[[5a2i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A2I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A2I FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a2j|5a2j]], [[5a2k|5a2k]], [[5a2l|5a2l]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a2i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a2i RCSB], [http://www.ebi.ac.uk/pdbsum/5a2i PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a2i OCA], [https://pdbe.org/5a2i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a2i RCSB], [https://www.ebi.ac.uk/pdbsum/5a2i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a2i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HVM32_MOUSE HVM32_MOUSE] [https://www.uniprot.org/uniprot/LV1E_MOUSE LV1E_MOUSE]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 5a2i" style="background-color:#fffaf0;"></div>
==See Also==
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Asensio, J L]]
[[Category: Homo sapiens]]
[[Category: Avenoza, A]]
[[Category: Large Structures]]
[[Category: Bernardes, G J.L]]
[[Category: Mus musculus]]
[[Category: Busto, J H]]
[[Category: Asensio JL]]
[[Category: Castro-Lopez, J]]
[[Category: Avenoza A]]
[[Category: Companon, I]]
[[Category: Bernardes GJL]]
[[Category: Corzana, F]]
[[Category: Busto JH]]
[[Category: Hurtado-Guerrero, R]]
[[Category: Castro-Lopez J]]
[[Category: Jimenez-Barbero, J]]
[[Category: Companon I]]
[[Category: Madariaga, D]]
[[Category: Corzana F]]
[[Category: Martinez-Saez, N]]
[[Category: Hurtado-Guerrero R]]
[[Category: Peregrina, J M]]
[[Category: Jimenez-Barbero J]]
[[Category: Salvado, M]]
[[Category: Madariaga D]]
[[Category: Somovilla, V J]]
[[Category: Martinez-Saez N]]
[[Category: Valero-Gonzalez, J]]
[[Category: Peregrina JM]]
[[Category: Antibody]]
[[Category: Salvado M]]
[[Category: Conformation analysis]]
[[Category: Somovilla VJ]]
[[Category: Fusion protein]]
[[Category: Valero-Gonzalez J]]
[[Category: Glycopeptide]]
[[Category: Immune system]]
[[Category: Molecular recognition]]

Latest revision as of 11:03, 10 January 2024

Crystal structure of scFv-SM3 in complex with APD-SGalNAc-RP

5a2i, resolution 1.88Å

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