4yw7: Difference between revisions

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'''Unreleased structure'''


The entry 4yw7 is ON HOLD  until Paper Publication
==Structural Insight into Divalent Galactoside Binding to Pseudomonas aeruginosa lectin LecA==
<StructureSection load='4yw7' size='340' side='right'caption='[[4yw7]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4yw7]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YW7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4J0:(2R,3R,4S,5R,6R,2R,3R,4S,5R,6R)-2,2-([(2R,3R,4S,5S,6S)-3,4-DIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2,5-DIYL]BIS{1H-1,2,3-TRIAZOLE-1,4-DIYL[(2S,3R,4S,5S,6S)-3,4-DIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2,5-DIYL]-1H-1,2,3-TRIAZOLE-1,4-DIYLPROPANE-3,1-DIYLOXY})BIS[6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL]'>4J0</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yw7 OCA], [https://pdbe.org/4yw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yw7 RCSB], [https://www.ebi.ac.uk/pdbsum/4yw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yw7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity.


Authors: Visini, R., Jin, X., Michaud, G., Bergmann, M., Gillon, E., Imberty, A., Stocker, A., Darbre, T., Pieters, R., Reymond, J.-L.
==See Also==
 
*[[Galactose-binding lectin|Galactose-binding lectin]]
Description: Structural Insight into Divalent Galactoside Binding to Pseudomonas aeruginosa lectin LecA
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Pieters, R]]
[[Category: Large Structures]]
[[Category: Michaud, G]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Gillon, E]]
[[Category: Bergmann M]]
[[Category: Bergmann, M]]
[[Category: Darbre T]]
[[Category: Imberty, A]]
[[Category: Gillon E]]
[[Category: Visini, R]]
[[Category: Imberty A]]
[[Category: Reymond, J.-L]]
[[Category: Jin X]]
[[Category: Darbre, T]]
[[Category: Michaud G]]
[[Category: Stocker, A]]
[[Category: Pieters R]]
[[Category: Jin, X]]
[[Category: Reymond J-L]]
[[Category: Stocker A]]
[[Category: Visini R]]
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