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==solution structure of cerebral dopamine neurotrophic factor (CDNF)==
==solution structure of cerebral dopamine neurotrophic factor (CDNF)==
<StructureSection load='4bit' size='340' side='right' caption='[[4bit]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='4bit' size='340' side='right'caption='[[4bit]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4bit]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BIT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BIT FirstGlance]. <br>
<table><tr><td colspan='2'>[[4bit]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BIT FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bit OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bit RCSB], [http://www.ebi.ac.uk/pdbsum/4bit PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bit OCA], [https://pdbe.org/4bit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bit RCSB], [https://www.ebi.ac.uk/pdbsum/4bit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bit ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CDNF_HUMAN CDNF_HUMAN]] Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity).  
[https://www.uniprot.org/uniprot/CDNF_HUMAN CDNF_HUMAN] Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4bit" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Almeida, m s]]
[[Category: Large Structures]]
[[Category: Cabral, k m.s]]
[[Category: Almeida MS]]
[[Category: Foguel, d]]
[[Category: Cabral KMS]]
[[Category: Herrmann, t]]
[[Category: Foguel D]]
[[Category: Latge, c]]
[[Category: Herrmann T]]
[[Category: Raymundo, d p]]
[[Category: Latge C]]
[[Category: Parkinson]]
[[Category: Raymundo DP]]
[[Category: Signaling protein]]
Retrieved from "https://proteopedia.org/4bit"