5cp8: Difference between revisions
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The | ==The effect of isoleucine to alanine mutation on InhA enzyme crystallization pattern and substrate binding loop conformation and flexibility== | ||
<StructureSection load='5cp8' size='340' side='right'caption='[[5cp8]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5cp8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CP8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CP8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=ETE:2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>ETE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCU:5-HEXYL-2-(2-METHYLPHENOXY)PHENOL'>TCU</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cp8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cp8 OCA], [https://pdbe.org/5cp8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cp8 RCSB], [https://www.ebi.ac.uk/pdbsum/5cp8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cp8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU] | |||
==See Also== | |||
*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Li | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: | [[Category: Bommineni GR]] | ||
[[Category: Tonge | [[Category: Garcia-Diaz M]] | ||
[[Category: Lai C-T]] | |||
[[Category: Li H-J]] | |||
[[Category: Liu N]] | |||
[[Category: Perrone V]] | |||
[[Category: Shah S]] | |||
[[Category: Simmerling C]] | |||
[[Category: Tonge PJ]] | |||
[[Category: Yu W]] | |||
Latest revision as of 12:20, 6 March 2024
The effect of isoleucine to alanine mutation on InhA enzyme crystallization pattern and substrate binding loop conformation and flexibility
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