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==Crystal Structure of H. influenzae TrmD in complex with sinefungin==
==Crystal Structure of H. influenzae TrmD in complex with sinefungin==
<StructureSection load='4yvh' size='340' side='right' caption='[[4yvh]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='4yvh' size='340' side='right'caption='[[4yvh]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4yvh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YVH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YVH FirstGlance]. <br>
<table><tr><td colspan='2'>[[4yvh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_Rd_KW20 Haemophilus influenzae Rd KW20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YVH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yvg|4yvg]], [[4yvi|4yvi]], [[4yvj|4yvj]], [[4yvk|4yvk]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yvh OCA], [https://pdbe.org/4yvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yvh RCSB], [https://www.ebi.ac.uk/pdbsum/4yvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yvh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yvh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4yvh RCSB], [http://www.ebi.ac.uk/pdbsum/4yvh PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN]] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]  
[https://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4yvh" style="background-color:#fffaf0;"></div>
==See Also==
*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ito, T]]
[[Category: Haemophilus influenzae Rd KW20]]
[[Category: Yokoyama, S]]
[[Category: Large Structures]]
[[Category: Yoshida, K]]
[[Category: Ito T]]
[[Category: Mtase]]
[[Category: Yokoyama S]]
[[Category: Spout]]
[[Category: Yoshida K]]
[[Category: Transferase]]

Latest revision as of 15:39, 8 November 2023

Crystal Structure of H. influenzae TrmD in complex with sinefungin

4yvh, resolution 1.60Å

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