5dcg: Difference between revisions
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New page: '''Unreleased structure''' The entry 5dcg is ON HOLD Authors: Parker, L.J., Parker, M.W., Morton, C.J. Description: Crystal Structure of WT Apo Human Glutathione Transferase Pi [[Categ... |
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==Crystal Structure of WT Apo Human Glutathione Transferase Pi== | |||
<StructureSection load='5dcg' size='340' side='right'caption='[[5dcg]], [[Resolution|resolution]] 2.01Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5dcg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DCG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DCG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dcg OCA], [https://pdbe.org/5dcg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dcg RCSB], [https://www.ebi.ac.uk/pdbsum/5dcg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dcg ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GSTP1_HUMAN GSTP1_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.<ref>PMID:21668448</ref> | |||
==See Also== | |||
*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: Parker | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | |||
[[Category: Morton CJ]] | |||
[[Category: Parker LJ]] | |||
[[Category: Parker MW]] | |||
Latest revision as of 08:45, 27 September 2023
Crystal Structure of WT Apo Human Glutathione Transferase Pi
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