4yw6: Difference between revisions
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==Structural Insight into Divalent Galactoside Binding to Pseudomonas aeruginosa lectin LecA== | ==Structural Insight into Divalent Galactoside Binding to Pseudomonas aeruginosa lectin LecA== | ||
<StructureSection load='4yw6' size='340' side='right' caption='[[4yw6]], [[Resolution|resolution]] 1.40Å' scene=''> | <StructureSection load='4yw6' size='340' side='right'caption='[[4yw6]], [[Resolution|resolution]] 1.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4yw6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YW6 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4yw6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YW6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YW6 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G0P:N-[(2S)-6-AMINO-1-OXO-1-(PYRROLIDIN-1-YL)HEXAN-2-YL]-4-(BETA-D-GALACTOPYRANOSYLOXY)BENZAMIDE'>G0P</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G0P:N-[(2S)-6-AMINO-1-OXO-1-(PYRROLIDIN-1-YL)HEXAN-2-YL]-4-(BETA-D-GALACTOPYRANOSYLOXY)BENZAMIDE'>G0P</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yw6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yw6 OCA], [https://pdbe.org/4yw6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yw6 RCSB], [https://www.ebi.ac.uk/pdbsum/4yw6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yw6 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 16: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4yw6" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Galactose-binding lectin|Galactose-binding lectin]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bergmann | [[Category: Large Structures]] | ||
[[Category: Darbre | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Gillon | [[Category: Bergmann M]] | ||
[[Category: Imberty | [[Category: Darbre T]] | ||
[[Category: Jin | [[Category: Gillon E]] | ||
[[Category: Michaud | [[Category: Imberty A]] | ||
[[Category: Pieters | [[Category: Jin X]] | ||
[[Category: Reymond | [[Category: Michaud G]] | ||
[[Category: Stocker | [[Category: Pieters R]] | ||
[[Category: Visini | [[Category: Reymond J-L]] | ||
[[Category: Stocker A]] | |||
[[Category: Visini R]] | |||
Latest revision as of 10:56, 10 January 2024
Structural Insight into Divalent Galactoside Binding to Pseudomonas aeruginosa lectin LecA
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