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==Crystal structure of non-symbiotic plant hemoglobin from rice, B10 mutant F40L==
==Crystal structure of non-symbiotic plant hemoglobin from rice, B10 mutant F40L==
<StructureSection load='2gnv' size='340' side='right' caption='[[2gnv]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2gnv' size='340' side='right'caption='[[2gnv]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gnv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Orysa Orysa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GNV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GNV FirstGlance]. <br>
<table><tr><td colspan='2'>[[2gnv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GNV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GNV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gnw|2gnw]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HB1, GLB1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4530 ORYSA])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gnv OCA], [https://pdbe.org/2gnv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gnv RCSB], [https://www.ebi.ac.uk/pdbsum/2gnv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gnv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gnv OCA], [http://pdbe.org/2gnv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gnv RCSB], [http://www.ebi.ac.uk/pdbsum/2gnv PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HBL1_ORYSJ HBL1_ORYSJ]] May not function as an oxygen storage or transport protein, but might act as an oxygen sensor or play a role in electron transfer, possibly to a bound oxygen molecule. Has an unusually high affinity for O(2) because of a very low dissociation constant.  
[https://www.uniprot.org/uniprot/NSHB1_ORYSJ NSHB1_ORYSJ] Phytoglobin that reduces nitrite to nitric oxide under anoxic conditions (e.g. during flooding or in waterlogged soil) (PubMed:21495624). May not function as an oxygen storage or transport protein (PubMed:17540516, PubMed:9390447). Has an unusually high affinity for O(2) through a hexacoordinate heme iron because of a very low dissociation constant (PubMed:9390447).<ref>PMID:21495624</ref> <ref>PMID:9390447</ref> <ref>PMID:17540516</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gn/2gnv_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gn/2gnv_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gnv ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Orysa]]
[[Category: Large Structures]]
[[Category: Hoy, J A]]
[[Category: Oryza sativa]]
[[Category: On 2 helical fold]]
[[Category: Hoy JA]]
[[Category: Globin]]
[[Category: Heme]]
[[Category: Hemoglobin]]
[[Category: Hexacoordinate]]
[[Category: Iron]]
[[Category: Nonsymbiotic]]
[[Category: Oxygen storage-transport complex]]
[[Category: Rice]]
Retrieved from "https://proteopedia.org/2gnv"