1s22: Difference between revisions

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[[Image:1s22.gif|left|200px]]


{{Structure
==Absolute Stereochemistry of Ulapualide A==
|PDB= 1s22 |SIZE=350|CAPTION= <scene name='initialview01'>1s22</scene>, resolution 1.60&Aring;
<StructureSection load='1s22' size='340' side='right'caption='[[1s22]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ATP:ADENOSINE-5&#39;-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=ULA:ULAPUALIDE+A'>ULA</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
<table><tr><td colspan='2'>[[1s22]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S22 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene>, <scene name='pdbligand=ULA:ULAPUALIDE+A'>ULA</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s22 OCA], [https://pdbe.org/1s22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s22 RCSB], [https://www.ebi.ac.uk/pdbsum/1s22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s22 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
[structure: see text] The structure of ulapualide A (1) has been solved by X-ray crystallography in a complex with G-actin. The stereochemical configuration was assigned as 3S,9S,22S,23R,24S,26S,27S,31R,32R,33R.


'''Absolute Stereochemistry of Ulapualide A'''
Absolute stereochemistry of ulapualide A.,Allingham JS, Tanaka J, Marriott G, Rayment I Org Lett. 2004 Feb 19;6(4):597-9. PMID:14961632<ref>PMID:14961632</ref>


From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 1s22" style="background-color:#fffaf0;"></div>


==Overview==
==See Also==
[structure: see text] The structure of ulapualide A (1) has been solved by X-ray crystallography in a complex with G-actin. The stereochemical configuration was assigned as 3S,9S,22S,23R,24S,26S,27S,31R,32R,33R.
*[[Actin 3D structures|Actin 3D structures]]
 
== References ==
==About this Structure==
<references/>
1S22 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S22 OCA].
__TOC__
 
</StructureSection>
==Reference==
[[Category: Large Structures]]
Absolute stereochemistry of ulapualide A., Allingham JS, Tanaka J, Marriott G, Rayment I, Org Lett. 2004 Feb 19;6(4):597-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14961632 14961632]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Single protein]]
[[Category: Allingham JS]]
[[Category: Allingham, J S.]]
[[Category: Marriott G]]
[[Category: Marriott, G.]]
[[Category: Rayment I]]
[[Category: Rayment, I.]]
[[Category: Tanaka J]]
[[Category: Tanaka, J.]]
[[Category: ATP]]
[[Category: CA]]
[[Category: EDO]]
[[Category: ULA]]
[[Category: actin; trisoxazole; macrolide; toxin; ulapualide; stereochemistry]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 13:33:24 2008''

Latest revision as of 21:34, 28 June 2023

Absolute Stereochemistry of Ulapualide A

1s22, resolution 1.60Å

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