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==Oxidized structure of the N-terminal domain of Salmonella typhimurium AhpF==
==Oxidized structure of the N-terminal domain of Salmonella typhimurium AhpF==
<StructureSection load='1zyn' size='340' side='right' caption='[[1zyn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1zyn' size='340' side='right'caption='[[1zyn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1zyn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZYN FirstGlance]. <br>
<table><tr><td colspan='2'>[[1zyn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZYN FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hyu|1hyu]], [[1zyp|1zyp]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zyn OCA], [http://pdbe.org/1zyn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zyn RCSB], [http://www.ebi.ac.uk/pdbsum/1zyn PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zyn OCA], [https://pdbe.org/1zyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zyn RCSB], [https://www.ebi.ac.uk/pdbsum/1zyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zyn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/AHPF_SALTY AHPF_SALTY]] Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.  
[https://www.uniprot.org/uniprot/AHPF_SALTY AHPF_SALTY] Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zy/1zyn_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zy/1zyn_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zyn ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Jonsson, T J]]
[[Category: Large Structures]]
[[Category: Karplus, P A]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Poole, L B]]
[[Category: Jonsson TJ]]
[[Category: Roberts, B R]]
[[Category: Karplus PA]]
[[Category: Wood, Z A]]
[[Category: Poole LB]]
[[Category: Oxidoreductase]]
[[Category: Roberts BR]]
[[Category: Thiolate]]
[[Category: Wood ZA]]