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==CRYSTAL STRUCTURE OF THE CONSERVED HYPOTHETICAL PROTEIN RV1873 FROM MYCOBACTERIUM TUBERCULOSIS AT 1.38 A==
 
<StructureSection load='2jek' size='340' side='right' caption='[[2jek]], [[Resolution|resolution]] 1.38&Aring;' scene=''>
==Crystal structure of the conserved hypothetical protein Rv1873 from Mycobacterium tuberculosis at 1.38 A==
<StructureSection load='2jek' size='340' side='right'caption='[[2jek]], [[Resolution|resolution]] 1.38&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2jek]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2d2y 2d2y]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JEK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JEK FirstGlance]. <br>
<table><tr><td colspan='2'>[[2jek]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2d2y 2d2y]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JEK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JEK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.38&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2d2y|2d2y]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jek OCA], [http://pdbe.org/2jek PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jek RCSB], [http://www.ebi.ac.uk/pdbsum/2jek PDBsum], [http://www.topsan.org/Proteins/TBSGC/2jek TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jek OCA], [https://pdbe.org/2jek PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jek RCSB], [https://www.ebi.ac.uk/pdbsum/2jek PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jek ProSAT], [https://www.topsan.org/Proteins/TBSGC/2jek TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O07756_MYCTU O07756_MYCTU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/2jek_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/2jek_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jek ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Myctu]]
[[Category: Large Structures]]
[[Category: Bergmann, E M]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Cherney, M M]]
[[Category: Bergmann EM]]
[[Category: Structural genomic]]
[[Category: Cherney MM]]
[[Category: Garen, C R]]
[[Category: Garen CR]]
[[Category: James, M N.G]]
[[Category: James MNG]]
[[Category: Hypothetical protein]]
[[Category: Mycobacterium tuberculosis]]
[[Category: PSI, Protein structure initiative]]
[[Category: Right-handed superhelix]]
[[Category: Tbsgc]]
[[Category: Unknown function]]

Latest revision as of 09:37, 9 May 2024

Crystal structure of the conserved hypothetical protein Rv1873 from Mycobacterium tuberculosis at 1.38 A

2jek, resolution 1.38Å

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