2oyl: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(13 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2oyl.jpg|left|200px]]


{{Structure
==Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like imidazole complex==
|PDB= 2oyl |SIZE=350|CAPTION= <scene name='initialview01'>2oyl</scene>, resolution 1.800&Aring;
<StructureSection load='2oyl' size='340' side='right'caption='[[2oyl]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=IDC:5-HYDROXYMETHYL-5,6,7,8-TETRAHYDRO-IMIDAZO[1,2-A]PYRIDIN-6YL-7,8-DIOL-GLUCOPYRANOSIDE'>IDC</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
<table><tr><td colspan='2'>[[2oyl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OYL FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Endoglycosylceramidase Endoglycosylceramidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.123 3.2.1.123]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IDC:5-HYDROXYMETHYL-5,6,7,8-TETRAHYDRO-IMIDAZO[1,2-A]PYRIDIN-6YL-7,8-DIOL-GLUCOPYRANOSIDE'>IDC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oyl OCA], [https://pdbe.org/2oyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oyl RCSB], [https://www.ebi.ac.uk/pdbsum/2oyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oyl ProSAT]</span></td></tr>
 
</table>
'''Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like imidazole complex'''
== Function ==
 
[https://www.uniprot.org/uniprot/O33853_RHOSO O33853_RHOSO]  
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2OYL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OYL OCA].
Check<jmol>
 
  <jmolCheckbox>
==Reference==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oy/2oyl_consurf.spt"</scriptWhenChecked>
The structural basis of glycosidase inhibition by five-membered iminocyclitols: the clan a glycoside hydrolase endoglycoceramidase as a model system., Caines ME, Hancock SM, Tarling CA, Wrodnigg TM, Stick RV, Stutz AE, Vasella A, Withers SG, Strynadka NC, Angew Chem Int Ed Engl. 2007;46(24):4474-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17487923 17487923]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Endoglycosylceramidase]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Rhodococcus sp.]]
  </jmolCheckbox>
[[Category: Single protein]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oyl ConSurf].
[[Category: Caines, M E.C.]]
<div style="clear:both"></div>
[[Category: Strynadka, N C.J.]]
__TOC__
[[Category: GOL]]
</StructureSection>
[[Category: IDC]]
[[Category: Large Structures]]
[[Category: NA]]
[[Category: Rhodococcus sp]]
[[Category: (alpha/beta)8 (tim) barrel]]
[[Category: Caines MEC]]
[[Category: hydrolase]]
[[Category: Strynadka NCJ]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:35:46 2008''

Latest revision as of 10:50, 30 August 2023

Endo-glycoceramidase II from Rhodococcus sp.: cellobiose-like imidazole complex

2oyl, resolution 1.80Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA