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==BEAN POD MOTTLE VIRUS (BPMV), MIDDLE COMPONENT==
==BEAN POD MOTTLE VIRUS (BPMV), MIDDLE COMPONENT==
<StructureSection load='1pgl' size='340' side='right' caption='[[1pgl]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1pgl' size='340' side='right'caption='[[1pgl]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1pgl]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bean-pod_mottle_virus_(strain_kentucky_g7) Bean-pod mottle virus (strain kentucky g7)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PGL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PGL FirstGlance]. <br>
<table><tr><td colspan='2'>[[1pgl]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bean-pod_mottle_virus_(strain_Kentucky_G7) Bean-pod mottle virus (strain Kentucky G7)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PGL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PGL FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bmv|1bmv]], [[1ny7|1ny7]], [[1pgw|1pgw]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pgl OCA], [http://pdbe.org/1pgl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1pgl RCSB], [http://www.ebi.ac.uk/pdbsum/1pgl PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pgl OCA], [https://pdbe.org/1pgl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pgl RCSB], [https://www.ebi.ac.uk/pdbsum/1pgl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pgl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/POL2_BPMV POL2_BPMV]] Movement protein: transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).  
[https://www.uniprot.org/uniprot/POL2_BPMV POL2_BPMV] Movement protein: transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pg/1pgl_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pg/1pgl_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pgl ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Ordered nucleic acid in an icosahedral virus was first visualized in the X-ray structure of the Picorna-like plant virus, Bean pod mottle virus (BPMV). Virus particles containing the 3500 nucleotide segment of the BPMV bipartite RNA genome (middle component) had nearly 20% of the genome ordered. Here we report the refined structures of the middle component, bottom component (particles containing the 5800 nucleotide segment of the genome), and top component (empty particles of BPMV capsid protein). The bottom component particles contain ordered RNA in the same location as middle component. Although the ordered RNA density in both nucleoprotein particles is the average of the contents of 60 icosahedral asymmetric units, both nucleoprotein components show that the base density for the first two nucleotides is predominantly purine, while the next five appear to be predominantly pyrimidine. The empty capsid demonstrates that RNA dictates the order of the N-terminal 19 residues of the large subunit because these residues are invisible in the top component.
Evidence for assembly-dependent folding of protein and RNA in an icosahedral virus.,Lin T, Cavarelli J, Johnson JE Virology. 2003 Sep 15;314(1):26-33. PMID:14517057<ref>PMID:14517057</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 1pgl" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Virus coat protein|Virus coat protein]]
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cavarelli, J]]
[[Category: Large Structures]]
[[Category: Johnson, J E]]
[[Category: Cavarelli J]]
[[Category: Lin, T]]
[[Category: Johnson JE]]
[[Category: Comovirus]]
[[Category: Lin T]]
[[Category: Icosahedral virus]]
[[Category: Viral coat protein]]
[[Category: Virus]]
[[Category: Virus-rna complex]]
Retrieved from "https://proteopedia.org/1pgl"