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==THE CRYSTAL STRUCTURE OF THE BACTERIAL CELL DIVISION PROTEIN ZAPA==
 
<StructureSection load='1w2e' size='340' side='right' caption='[[1w2e]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
==The Crystal Structure of the Bacterial Cell Division Protein ZapA==
<StructureSection load='1w2e' size='340' side='right'caption='[[1w2e]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1w2e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W2E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W2E FirstGlance]. <br>
<table><tr><td colspan='2'>[[1w2e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W2E FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1t3u|1t3u]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w2e OCA], [http://pdbe.org/1w2e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1w2e RCSB], [http://www.ebi.ac.uk/pdbsum/1w2e PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w2e OCA], [https://pdbe.org/1w2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w2e RCSB], [https://www.ebi.ac.uk/pdbsum/1w2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w2e ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ZAPA_PSEAE ZAPA_PSEAE]] Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity).  
[https://www.uniprot.org/uniprot/ZAPA_PSEAE ZAPA_PSEAE] Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w2/1w2e_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w2/1w2e_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w2e ConSurf].
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<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
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</div>
</div>
<div class="pdbe-citations 1w2e" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1w2e" style="background-color:#fffaf0;"></div>
==See Also==
*[[Cell division protein 3D structures|Cell division protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Low, H H]]
[[Category: Large Structures]]
[[Category: Lowe, J]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Moncrieffe, M C]]
[[Category: Low HH]]
[[Category: Bacterial cell division]]
[[Category: Lowe J]]
[[Category: Ftsz modulator]]
[[Category: Moncrieffe MC]]
Retrieved from "https://proteopedia.org/1w2e"