1gxp: Difference between revisions

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==PHOB EFFECTOR DOMAIN IN COMPLEX WITH PHO BOX DNA.==
 
<StructureSection load='1gxp' size='340' side='right' caption='[[1gxp]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
==PhoB effector domain in complex with pho box DNA.==
<StructureSection load='1gxp' size='340' side='right'caption='[[1gxp]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1gxp]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GXP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GXP FirstGlance]. <br>
<table><tr><td colspan='2'>[[1gxp]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The October 2015 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Two-component Systems''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2015_10 10.2210/rcsb_pdb/mom_2015_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GXP FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1b00|1b00]], [[1gxq|1gxq]], [[1qqi|1qqi]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gxp OCA], [http://pdbe.org/1gxp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gxp RCSB], [http://www.ebi.ac.uk/pdbsum/1gxp PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gxp OCA], [https://pdbe.org/1gxp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gxp RCSB], [https://www.ebi.ac.uk/pdbsum/1gxp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gxp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PHOB_ECOLI PHOB_ECOLI]] This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.  
[https://www.uniprot.org/uniprot/PHOB_ECOLI PHOB_ECOLI] This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gx/1gxp_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gx/1gxp_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gxp ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Blanco, A G]]
[[Category: Large Structures]]
[[Category: Coll, M]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Gomis-Ruth, F X]]
[[Category: Two-component Systems]]
[[Category: Sola, M]]
[[Category: Blanco AG]]
[[Category: Activator]]
[[Category: Coll M]]
[[Category: Dna binding]]
[[Category: Gomis-Ruth FX]]
[[Category: Helix-winged-helix]]
[[Category: Sola M]]
[[Category: Phosphorylation]]
[[Category: Sensory transduction]]
[[Category: Transcriptional activator]]
[[Category: Two- component signal transduction]]

Latest revision as of 08:51, 9 May 2024

PhoB effector domain in complex with pho box DNA.

1gxp, resolution 2.50Å

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