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[[Image:3b6v.gif|left|200px]]


{{Structure
==Crystal structure of the motor domain of human kinesin family member 3C in complex with ADP==
|PDB= 3b6v |SIZE=350|CAPTION= <scene name='initialview01'>3b6v</scene>, resolution 2.700&Aring;
<StructureSection load='3b6v' size='340' side='right'caption='[[3b6v]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Mg+Binding+Site+For+Residue+A+1002'>AC1</scene>, <scene name='pdbsite=AC2:Mg+Binding+Site+For+Residue+B+1002'>AC2</scene>, <scene name='pdbsite=AC3:Adp+Binding+Site+For+Residue+A+1001'>AC3</scene>, <scene name='pdbsite=AC4:Adp+Binding+Site+For+Residue+B+1001'>AC4</scene>, <scene name='pdbsite=AC5:Unx+Binding+Site+For+Residue+B+1003'>AC5</scene>, <scene name='pdbsite=AC6:Unx+Binding+Site+For+Residue+A+1003'>AC6</scene>, <scene name='pdbsite=AC7:Unx+Binding+Site+For+Residue+A+1004'>AC7</scene>, <scene name='pdbsite=AC8:Unx+Binding+Site+For+Residue+B+1004'>AC8</scene>, <scene name='pdbsite=AC9:Unx+Binding+Site+For+Residue+B+1005'>AC9</scene>, <scene name='pdbsite=BC1:Unx+Binding+Site+For+Residue+B+1006'>BC1</scene>, <scene name='pdbsite=BC2:Unx+Binding+Site+For+Residue+A+1005'>BC2</scene> and <scene name='pdbsite=BC3:Unx+Binding+Site+For+Residue+B+1007'>BC3</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ADP:ADENOSINE-5&#39;-DIPHOSPHATE'>ADP</scene> and <scene name='pdbligand=UNX:UNKNOWN ATOM OR ION'>UNX</scene>
<table><tr><td colspan='2'>[[3b6v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B6V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B6V FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
|GENE= KIF3C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b6v OCA], [https://pdbe.org/3b6v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b6v RCSB], [https://www.ebi.ac.uk/pdbsum/3b6v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b6v ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KIF3C_HUMAN KIF3C_HUMAN] Microtubule-based anterograde translocator for membranous organelles (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/3b6v_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b6v ConSurf].
<div style="clear:both"></div>


'''Crystal structure of the motor domain of human kinesin family member 3C in complex with ADP'''
==See Also==
 
*[[Kinesin 3D Structures|Kinesin 3D Structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3B6V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B6V OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Bochkarev, A.]]
[[Category: Bochkarev A]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Landry, R.]]
[[Category: Landry R]]
[[Category: Park, H.]]
[[Category: Park H]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Shen Y]]
[[Category: Shen, Y.]]
[[Category: Sundstrom M]]
[[Category: Sundstrom, M.]]
[[Category: Tempel W]]
[[Category: Tempel, W.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Zhu H]]
[[Category: Zhu, H.]]
[[Category: ADP]]
[[Category: MG]]
[[Category: UNX]]
[[Category: adp]]
[[Category: atp-binding]]
[[Category: coiled coil]]
[[Category: kinesin]]
[[Category: microtubule]]
[[Category: motor domain]]
[[Category: motor protein]]
[[Category: nucleotide-binding]]
[[Category: sgc]]
[[Category: structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:58:32 2008''
Retrieved from "https://proteopedia.org/3b6v"