5ukd: Difference between revisions

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[[Image:5ukd.gif|left|200px]]


{{Structure
==PH INFLUENCES FLUORIDE COORDINATION NUMBER OF THE ALFX PHOSPHORYL TRANSFER TRANSITION STATE ANALOG==
|PDB= 5ukd |SIZE=350|CAPTION= <scene name='initialview01'>5ukd</scene>, resolution 1.9&Aring;
<StructureSection load='5ukd' size='340' side='right'caption='[[5ukd]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ADP:ADENOSINE-5&#39;-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=C5P:CYTIDINE-5&#39;-MONOPHOSPHATE'>C5P</scene> and <scene name='pdbligand=AF3:ALUMINUM FLUORIDE'>AF3</scene>
<table><tr><td colspan='2'>[[5ukd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UKD FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Cytidylate_kinase Cytidylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.14 2.7.4.14]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
|GENE= KCY_DICDI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=44689 Dictyostelium discoideum])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=AF3:ALUMINUM+FLUORIDE'>AF3</scene>, <scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ukd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ukd OCA], [https://pdbe.org/5ukd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ukd RCSB], [https://www.ebi.ac.uk/pdbsum/5ukd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ukd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KCY_DICDI KCY_DICDI] This UMP-CMP kinase uses preferentially ATP as phosphate donor and is specific for UMP and CMP.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uk/5ukd_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=5ukd ConSurf].
<div style="clear:both"></div>


'''PH INFLUENCES FLUORIDE COORDINATION NUMBER OF THE ALFX PHOSPHORYL TRANSFER TRANSITION STATE ANALOG'''
==See Also==
 
*[[UMP/CMP kinase|UMP/CMP kinase]]
 
__TOC__
==About this Structure==
</StructureSection>
5UKD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UKD OCA].
 
==Reference==
pH influences fluoride coordination number of the AlFx phosphoryl transfer transition state analog., Schlichting I, Reinstein J, Nat Struct Biol. 1999 Aug;6(8):721-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10426946 10426946]
[[Category: Cytidylate kinase]]
[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Reinstein, J.]]
[[Category: Reinstein J]]
[[Category: Schlichting, I.]]
[[Category: Schlichting I]]
[[Category: ADP]]
[[Category: AF3]]
[[Category: C5P]]
[[Category: MG]]
[[Category: nmp kinase]]
[[Category: nucleoside monophosphate kinase]]
[[Category: phosphoryl transfer]]
[[Category: transferase]]
[[Category: transition state analog complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 16:05:46 2008''
Retrieved from "https://proteopedia.org/5ukd"