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==Crystal structure of monoclinic form of genomically encoded fosfomycin resistance protein, FosX, from Listeria monocytogenes at pH 6.5==
==Crystal structure of monoclinic form of genomically encoded fosfomycin resistance protein, FosX, from Listeria monocytogenes at pH 6.5==
<StructureSection load='2p7m' size='340' side='right' caption='[[2p7m]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='2p7m' size='340' side='right'caption='[[2p7m]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2p7m]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Lismo Lismo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P7M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2P7M FirstGlance]. <br>
<table><tr><td colspan='2'>[[2p7m]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes_EGD-e Listeria monocytogenes EGD-e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P7M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P7M FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2p7k|2p7k]], [[2p7l|2p7l]], [[2p7o|2p7o]], [[2p7p|2p7p]], [[2p7q|2p7q]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p7m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p7m OCA], [http://pdbe.org/2p7m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2p7m RCSB], [http://www.ebi.ac.uk/pdbsum/2p7m PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p7m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p7m OCA], [https://pdbe.org/2p7m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p7m RCSB], [https://www.ebi.ac.uk/pdbsum/2p7m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p7m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FOSX_LISMO FOSX_LISMO] Catalyzes the hydration of fosfomycin.<ref>PMID:14677948</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p7/2p7m_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p7/2p7m_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p7m ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lismo]]
[[Category: Large Structures]]
[[Category: Armstrong, R N]]
[[Category: Listeria monocytogenes EGD-e]]
[[Category: Fillgrove, K L]]
[[Category: Armstrong RN]]
[[Category: Newcomer, M E]]
[[Category: Fillgrove KL]]
[[Category: Pakhomova, S]]
[[Category: Newcomer ME]]
[[Category: Schaab, M]]
[[Category: Pakhomova S]]
[[Category: Antibiotic resistance]]
[[Category: Schaab M]]
[[Category: Fosfomycin resistance protein]]
[[Category: Hydrolase]]
[[Category: Metal binding protein]]
[[Category: Mn binding]]
Retrieved from "https://proteopedia.org/2p7m"