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[[Image:2prr.jpg|left|200px]]


{{Structure
==Crystal structure of alkylhydroperoxidase AhpD core: uncharacterized peroxidase-related protein (YP_296737.1) from Ralstonia eutropha JMP134 at 2.15 A resolution==
|PDB= 2prr |SIZE=350|CAPTION= <scene name='initialview01'>2prr</scene>, resolution 2.150&Aring;
<StructureSection load='2prr' size='340' side='right'caption='[[2prr]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>
<table><tr><td colspan='2'>[[2prr]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Cupriavidus_pinatubonensis_JMP134 Cupriavidus pinatubonensis JMP134]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PRR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PRR FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
|GENE= YP_296737.1, Reut_A2532 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=264198 Ralstonia eutropha JMP134])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG2128 COG2128]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2prr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2prr OCA], [https://pdbe.org/2prr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2prr RCSB], [https://www.ebi.ac.uk/pdbsum/2prr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2prr ProSAT], [https://www.topsan.org/Proteins/JCSG/2prr TOPSAN]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2prr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2prr OCA], [http://www.ebi.ac.uk/pdbsum/2prr PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2prr RCSB]</span>
</table>
}}
== Function ==
 
[https://www.uniprot.org/uniprot/Q46Y90_CUPPJ Q46Y90_CUPPJ] Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.[SAAS:SAAS00088543]
'''Crystal structure of alkylhydroperoxidase AhpD core: uncharacterized peroxidase-related protein (YP_296737.1) from Ralstonia eutropha JMP134 at 2.15 A resolution'''
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
==About this Structure==
  <jmolCheckbox>
2PRR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Ralstonia_eutropha_jmp134 Ralstonia eutropha jmp134]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PRR OCA].  
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pr/2prr_consurf.spt"</scriptWhenChecked>
[[Category: Ralstonia eutropha jmp134]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Single protein]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: JCSG, Joint Center for Structural Genomics.]]
  </jmolCheckbox>
[[Category: alkylhydroperoxidase ahpd core: uncharacterized peroxidase-related]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2prr ConSurf].
[[Category: carboxymuconolactone decarboxylase family]]
<div style="clear:both"></div>
[[Category: jcsg]]
__TOC__
[[Category: joint center for structural genomic]]
</StructureSection>
[[Category: protein structure initiative]]
[[Category: Cupriavidus pinatubonensis JMP134]]
[[Category: psi-2]]
[[Category: Large Structures]]
[[Category: structural genomic]]
[[Category: yp_296737 1]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Mar 25 23:33:43 2008''

Latest revision as of 08:30, 30 October 2024

Crystal structure of alkylhydroperoxidase AhpD core: uncharacterized peroxidase-related protein (YP_296737.1) from Ralstonia eutropha JMP134 at 2.15 A resolution

2prr, resolution 2.15Å

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