2r3e: Difference between revisions

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[[Image:2r3e.jpg|left|200px]]


{{Structure
==CRYSTAL STRUCTURE OF a ribokinase-like superfamily protein (EF1790) FROM ENTEROCOCCUS FAECALIS V583 AT 1.95 A RESOLUTION==
|PDB= 2r3e |SIZE=350|CAPTION= <scene name='initialview01'>2r3e</scene>, resolution 1.950&Aring;
<StructureSection load='2r3e' size='340' side='right'caption='[[2r3e]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
<table><tr><td colspan='2'>[[2r3e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_V583 Enterococcus faecalis V583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R3E FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
|GENE= NP_815490.1, EF_1790 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=226185 Enterococcus faecalis V583])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01171 YXKO-related]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r3e OCA], [https://pdbe.org/2r3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r3e RCSB], [https://www.ebi.ac.uk/pdbsum/2r3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r3e ProSAT], [https://www.topsan.org/Proteins/JCSG/2r3e TOPSAN]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r3e OCA], [http://www.ebi.ac.uk/pdbsum/2r3e PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2r3e RCSB]</span>
</table>
}}
== Function ==
 
[https://www.uniprot.org/uniprot/NNRD_ENTFA NNRD_ENTFA] Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.[HAMAP-Rule:MF_01965]
'''Crystal structure of a putative kinase in the ribokinase-like superfamily from Enterococcus faecalis V583 (NP_815490.1) at 1.95 A resolution'''
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
==About this Structure==
  <jmolCheckbox>
2R3E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis_v583 Enterococcus faecalis v583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R3E OCA].  
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r3/2r3e_consurf.spt"</scriptWhenChecked>
[[Category: Enterococcus faecalis v583]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Single protein]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: JCSG, Joint Center for Structural Genomics.]]
  </jmolCheckbox>
[[Category: jcsg]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r3e ConSurf].
[[Category: joint center for structural genomic]]
<div style="clear:both"></div>
[[Category: np_815490 1]]
__TOC__
[[Category: protein structure initiative]]
</StructureSection>
[[Category: psi-2]]
[[Category: Enterococcus faecalis V583]]
[[Category: putative kinase in the ribokinase-like superfamily from enterococcus faecalis v583]]
[[Category: Large Structures]]
[[Category: structural genomic]]
[[Category: transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Mar 25 23:35:20 2008''
Retrieved from "https://proteopedia.org/2r3e"