1l7a: Difference between revisions

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[[Image:1l7a.gif|left|200px]]


{{Structure
==structural Genomics, crystal structure of Cephalosporin C deacetylase==
|PDB= 1l7a |SIZE=350|CAPTION= <scene name='initialview01'>1l7a</scene>, resolution 1.50&Aring;
<StructureSection load='1l7a' size='340' side='right'caption='[[1l7a]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1l7a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L7A FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Cephalosporin-C_deacetylase Cephalosporin-C deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.41 3.1.1.41] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
|GENE= CAH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l7a OCA], [https://pdbe.org/1l7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l7a RCSB], [https://www.ebi.ac.uk/pdbsum/1l7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l7a ProSAT], [https://www.topsan.org/Proteins/MCSG/1l7a TOPSAN]</span></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam05448 AXE1]</span>
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l7a OCA], [http://www.ebi.ac.uk/pdbsum/1l7a PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1l7a RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/CAH_BACSU CAH_BACSU] Esterase that removed acetyl groups from a number of O-acetylated small substrates, such as acetylated xylose, short xylooligosaccharides and cephalosporin C. Has no activity towards polymeric acetylated xylan. Cannot cleave amide linkages.<ref>PMID:12842474</ref>
 
== Evolutionary Conservation ==
'''structural Genomics, crystal structure of Cephalosporin C deacetylase'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l7/1l7a_consurf.spt"</scriptWhenChecked>
1L7A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L7A OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l7a ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Cephalosporin-C deacetylase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Collert F]]
[[Category: Collert, F.]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, A.]]
[[Category: Koroleva O]]
[[Category: Koroleva, O.]]
[[Category: Zhang R]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Zhang, R.]]
[[Category: alpha-beta-alpha sandwich]]
[[Category: mcsg]]
[[Category: midwest center for structural genomic]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
 
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Retrieved from "https://proteopedia.org/1l7a"