1lv3: Difference between revisions

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[[Image:1lv3.gif|left|200px]]


{{Structure
==Solution NMR Structure of Zinc Finger Protein yacG from Escherichia coli. Northeast Structural Genomics Consortium Target ET92.==
|PDB= 1lv3 |SIZE=350|CAPTION= <scene name='initialview01'>1lv3</scene>
<StructureSection load='1lv3' size='340' side='right'caption='[[1lv3]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[1lv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LV3 FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= yacG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK00418 PRK00418]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lv3 OCA], [https://pdbe.org/1lv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lv3 RCSB], [https://www.ebi.ac.uk/pdbsum/1lv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lv3 ProSAT], [https://www.topsan.org/Proteins/NESGC/1lv3 TOPSAN]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lv3 OCA], [http://www.ebi.ac.uk/pdbsum/1lv3 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1lv3 RCSB]</span>
</table>
}}
== Function ==
 
[https://www.uniprot.org/uniprot/YACG_ECOLI YACG_ECOLI] Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.<ref>PMID:18586829</ref>
'''Solution NMR Structure of Zinc Finger Protein yacG from Escherichia coli. Northeast Structural Genomics Consortium Target ET92.'''
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
==About this Structure==
  <jmolCheckbox>
1LV3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LV3 OCA].  
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/1lv3_consurf.spt"</scriptWhenChecked>
 
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
==Reference==
    <text>to colour the structure by Evolutionary Conservation</text>
NMR structure of the Escherichia coli protein YacG: a novel sequence motif in the zinc-finger family of proteins., Ramelot TA, Cort JR, Yee AA, Semesi A, Edwards AM, Arrowsmith CH, Kennedy MA, Proteins. 2002 Nov 1;49(2):289-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12211008 12211008]
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lv3 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Cort, J R.]]
[[Category: Cort JR]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Kennedy, M A.]]
[[Category: Kennedy MA]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Ramelot TA]]
[[Category: Ramelot, T A.]]
[[Category: Semesi A]]
[[Category: Semesi, A.]]
[[Category: Yee AA]]
[[Category: Yee, A A.]]
[[Category: antiparallel beta strand and alpha helix]]
[[Category: c4 tetrahedral zn+2]]
[[Category: et92]]
[[Category: nesg project]]
[[Category: northeast structural genomics consortium]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: rubredoxin knuckle]]
[[Category: structural genomic]]
[[Category: zinc finger]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 05:56:18 2008''
Retrieved from "https://proteopedia.org/1lv3"