1mzh: Difference between revisions

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[[Image:1mzh.gif|left|200px]]


{{Structure
==QR15, an Aldolase==
|PDB= 1mzh |SIZE=350|CAPTION= <scene name='initialview01'>1mzh</scene>, resolution 2.00&Aring;
<StructureSection load='1mzh' size='340' side='right'caption='[[1mzh]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
<table><tr><td colspan='2'>[[1mzh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MZH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MZH FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxyribose-phosphate_aldolase Deoxyribose-phosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.4 4.1.2.4] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00959 DeoC]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mzh OCA], [https://pdbe.org/1mzh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mzh RCSB], [https://www.ebi.ac.uk/pdbsum/1mzh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mzh ProSAT], [https://www.topsan.org/Proteins/NESGC/1mzh TOPSAN]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mzh OCA], [http://www.ebi.ac.uk/pdbsum/1mzh PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1mzh RCSB]</span>
</table>
}}
== Function ==
[https://www.uniprot.org/uniprot/DEOC_AQUAE DEOC_AQUAE] Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mz/1mzh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mzh ConSurf].
<div style="clear:both"></div>


'''QR15, an Aldolase'''
==See Also==
 
*[[Aldolase 3D structures|Aldolase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1MZH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MZH OCA].
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
[[Category: Deoxyribose-phosphate aldolase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Acton T]]
[[Category: Acton, T.]]
[[Category: Hunt JF]]
[[Category: Hunt, J F.]]
[[Category: Montelione G]]
[[Category: Montelione, G.]]
[[Category: Rost B]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Shen J]]
[[Category: Rost, B.]]
[[Category: Smith PC]]
[[Category: Shen, J.]]
[[Category: Tan AY]]
[[Category: Smith, P C.]]
[[Category: Xiao R]]
[[Category: Tan, A Y.]]
[[Category: Xiao, R.]]
[[Category: alpha-beta barrel]]
[[Category: nesg]]
[[Category: northeast structural genomics consortium]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 05:57:28 2008''

Latest revision as of 07:50, 14 February 2024

QR15, an Aldolase

1mzh, resolution 2.00Å

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