1n0f: Difference between revisions

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[[Image:1n0f.gif|left|200px]]


{{Structure
==CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF==
|PDB= 1n0f |SIZE=350|CAPTION= <scene name='initialview01'>1n0f</scene>, resolution 2.80&Aring;
<StructureSection load='1n0f' size='340' side='right'caption='[[1n0f]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1n0f]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N0F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N0F FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n0f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n0f OCA], [https://pdbe.org/1n0f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n0f RCSB], [https://www.ebi.ac.uk/pdbsum/1n0f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n0f ProSAT], [https://www.topsan.org/Proteins/BSGC/1n0f TOPSAN]</span></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam02381 MraZ]</span>
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n0f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n0f OCA], [http://www.ebi.ac.uk/pdbsum/1n0f PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1n0f RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/MRAZ_MYCPN MRAZ_MYCPN]
 
== Evolutionary Conservation ==
'''CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==Overview==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n0/1n0f_consurf.spt"</scriptWhenChecked>
UPF0040 is a family of proteins implicated in a cellular function of bacteria cell division. There is no structure information available on protein of this family. We have determined the crystal structure of a protein from Mycoplasma pneumoniae that belongs to this family using X-ray crystallography. Structural homology search reveals that this protein has a novel fold with no significant similarity to any proteins of known three-dimensional structure. The crystal structures of the protein in three different crystal forms reveal that the protein exists as a ring of octamer. The conserved protein residues, including a highly conserved DXXXR motif, are examined on the basis of crystal structure.
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1N0F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycoplasma_pneumoniae Mycoplasma pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N0F OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n0f ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif., Chen S, Jancrick J, Yokota H, Kim R, Kim SH, Proteins. 2004 Jun 1;55(4):785-91. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15146477 15146477]
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycoplasma pneumoniae]]
[[Category: Mycoplasma pneumoniae]]
[[Category: Single protein]]
[[Category: Chen S]]
[[Category: BSGC, Berkeley Structural Genomics Center.]]
[[Category: Jancrick J]]
[[Category: Chen, S.]]
[[Category: Kim R]]
[[Category: Jancrick, J.]]
[[Category: Kim S-H]]
[[Category: Kim, R.]]
[[Category: Yokota H]]
[[Category: Kim, S H.]]
[[Category: Yokota, H.]]
[[Category: berkeley structural genomics center]]
[[Category: bsgc structure funded by nih]]
[[Category: cell division]]
[[Category: cell wall biosynthesis protein]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
 
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