2f2i: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Solution structure of [P20D,V21K]-kalata B1==
==Solution structure of [P20D,V21K]-kalata B1==
<StructureSection load='2f2i' size='340' side='right' caption='[[2f2i]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2f2i' size='340' side='right'caption='[[2f2i]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2f2i]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F2I FirstGlance]. <br>
<table><tr><td colspan='2'>[[2f2i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oldenlandia_affinis Oldenlandia affinis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F2I FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2f2j|2f2j]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2i OCA], [http://pdbe.org/2f2i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2f2i RCSB], [http://www.ebi.ac.uk/pdbsum/2f2i PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2i OCA], [https://pdbe.org/2f2i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f2i RCSB], [https://www.ebi.ac.uk/pdbsum/2f2i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f2i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KAB1_OLDAF KAB1_OLDAF]] Probably participates in a plant defense mechanism. Has antibiotic activity. Has a diuretic effect. Has a uterotonic effect in humans. Active against the Gram-positive S.aureus with a minimum inhibition concentration of approximately 0.2 microM. Relatively ineffective against Gram-negative bacteria such as E.coli and P.aeruginosa. Inhibitory effect on the growth and development of larvae from H.punctigera. The unmodified form has hemolytic activity, the oxidized form lacks hemolytic activity. If the protein is linearized, hemolytic activity is lost.<ref>PMID:17534989</ref> <ref>PMID:12779323</ref>
[https://www.uniprot.org/uniprot/KAB1_OLDAF KAB1_OLDAF] Probably participates in a plant defense mechanism. Has antibiotic activity. Has a diuretic effect. Has a uterotonic effect in humans. Active against the Gram-positive S.aureus with a minimum inhibition concentration of approximately 0.2 microM. Relatively ineffective against Gram-negative bacteria such as E.coli and P.aeruginosa. Inhibitory effect on the growth and development of larvae from H.punctigera. The unmodified form has hemolytic activity, the oxidized form lacks hemolytic activity. If the protein is linearized, hemolytic activity is lost.<ref>PMID:17534989</ref> <ref>PMID:12779323</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Clark, R J]]
[[Category: Large Structures]]
[[Category: Craik, D J]]
[[Category: Oldenlandia affinis]]
[[Category: Daly, N L]]
[[Category: Clark RJ]]
[[Category: Antimicrobial protein]]
[[Category: Craik DJ]]
[[Category: Beta-hairpin]]
[[Category: Daly NL]]
[[Category: Circular backbone]]
[[Category: Cystine knot]]