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==Crystal structure of the bacterial antitoxin HigA from Escherichia coli at pH 8.5. Northeast Structural Genomics TARGET ER390.==
==Crystal structure of the bacterial antitoxin HigA from Escherichia coli at pH 8.5. Northeast Structural Genomics TARGET ER390.==
<StructureSection load='2ict' size='340' side='right' caption='[[2ict]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
<StructureSection load='2ict' size='340' side='right'caption='[[2ict]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ict]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecol6 Ecol6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ICT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ICT FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ict]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_CFT073 Escherichia coli CFT073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ICT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ICT FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2icp|2icp]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">higa ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=199310 ECOL6])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ict FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ict OCA], [https://pdbe.org/2ict PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ict RCSB], [https://www.ebi.ac.uk/pdbsum/2ict PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ict ProSAT], [https://www.topsan.org/Proteins/NESGC/2ict TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ict FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ict OCA], [http://pdbe.org/2ict PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ict RCSB], [http://www.ebi.ac.uk/pdbsum/2ict PDBsum], [http://www.topsan.org/Proteins/NESGC/2ict TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/YDDM_ECOL6 YDDM_ECOL6]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ic/2ict_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ic/2ict_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ict ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecol6]]
[[Category: Escherichia coli CFT073]]
[[Category: Abashidze, M]]
[[Category: Large Structures]]
[[Category: Acton, T B]]
[[Category: Abashidze M]]
[[Category: Arbing, M A]]
[[Category: Acton TB]]
[[Category: Baran, M C]]
[[Category: Arbing MA]]
[[Category: Cunningham, K]]
[[Category: Baran MC]]
[[Category: Hunt, J F]]
[[Category: Cunningham K]]
[[Category: Hurley, J M]]
[[Category: Hunt JF]]
[[Category: Inouye, M]]
[[Category: Hurley JM]]
[[Category: Janjua, H]]
[[Category: Inouye M]]
[[Category: Liu, J]]
[[Category: Janjua H]]
[[Category: Ma, L C]]
[[Category: Liu J]]
[[Category: Montelione, G T]]
[[Category: Ma LC]]
[[Category: Structural genomic]]
[[Category: Montelione GT]]
[[Category: Rost, B]]
[[Category: Rost B]]
[[Category: Woychik, N A]]
[[Category: Woychik NA]]
[[Category: Xiao, R]]
[[Category: Xiao R]]
[[Category: Zhao, L]]
[[Category: Zhao L]]
[[Category: Dna binding protein]]
[[Category: Helix-turn-helix]]
[[Category: Nesg]]
[[Category: PSI, Protein structure initiative]]

Latest revision as of 01:03, 21 November 2024

Crystal structure of the bacterial antitoxin HigA from Escherichia coli at pH 8.5. Northeast Structural Genomics TARGET ER390.

2ict, resolution 1.63Å

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