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[[Image:1vk5.gif|left|200px]]


{{Structure
==X-ray Structure of Gene Product from Arabidopsis Thaliana At3g22680==
|PDB= 1vk5 |SIZE=350|CAPTION= <scene name='initialview01'>1vk5</scene>, resolution 1.604&Aring;
<StructureSection load='1vk5' size='340' side='right'caption='[[1vk5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+300'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+A+301'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+A+302'>AC3</scene>, <scene name='pdbsite=AC4:Cps+Binding+Site+For+Residue+A+200'>AC4</scene>, <scene name='pdbsite=AC5:Edo+Binding+Site+For+Residue+A+401'>AC5</scene>, <scene name='pdbsite=AC6:Edo+Binding+Site+For+Residue+A+402'>AC6</scene>, <scene name='pdbsite=AC7:Edo+Binding+Site+For+Residue+A+403'>AC7</scene> and <scene name='pdbsite=AC8:Edo+Binding+Site+For+Residue+A+404'>AC8</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CPS:3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE'>CPS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
<table><tr><td colspan='2'>[[1vk5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VK5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VK5 FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.604&#8491;</td></tr>
|GENE= At3g22680 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CPS:3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE'>CPS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam09187 DUF1950]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vk5 OCA], [https://pdbe.org/1vk5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vk5 RCSB], [https://www.ebi.ac.uk/pdbsum/1vk5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vk5 ProSAT], [https://www.topsan.org/Proteins/CESG/1vk5 TOPSAN]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vk5 OCA], [http://www.ebi.ac.uk/pdbsum/1vk5 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1vk5 RCSB]</span>
</table>
}}
== Function ==
 
[https://www.uniprot.org/uniprot/RDM1_ARATH RDM1_ARATH] Regulator of RNA-directed DNA methylation (RdDM). Binds to single-stranded methyl DNA. Involved in the assembly of RNA polymerase V (Pol V) transcription initiation or elongation complexes at the chromatin, as a componant of the DDR complex.<ref>PMID:20409711</ref> <ref>PMID:20410883</ref> <ref>PMID:22864289</ref>
'''X-ray Structure of Gene Product from Arabidopsis Thaliana At3g22680'''
<div style="background-color:#fffaf0;">
 
== Publication Abstract from PubMed ==
 
==Overview==
The gene product of At3g22680 from Arabidopsis thaliana codes for a protein of unknown function. The crystal structure of the At3g22680 gene product was determined by multiple-wavelength anomalous diffraction and refined to an R factor of 16.0% (Rfree = 18.4%) at 1.60 A resolution. The refined structure shows one monomer in the asymmetric unit, with one molecule of the non-denaturing detergent CHAPS {3-[(3-cholamidopropyl)dimethylammonio]-1-propane sulfonate} tightly bound. Protein At3g22680 shows no structural homology to any other known proteins and represents a new fold in protein conformation space.
The gene product of At3g22680 from Arabidopsis thaliana codes for a protein of unknown function. The crystal structure of the At3g22680 gene product was determined by multiple-wavelength anomalous diffraction and refined to an R factor of 16.0% (Rfree = 18.4%) at 1.60 A resolution. The refined structure shows one monomer in the asymmetric unit, with one molecule of the non-denaturing detergent CHAPS {3-[(3-cholamidopropyl)dimethylammonio]-1-propane sulfonate} tightly bound. Protein At3g22680 shows no structural homology to any other known proteins and represents a new fold in protein conformation space.


==About this Structure==
Structure at 1.6 A resolution of the protein from gene locus At3g22680 from Arabidopsis thaliana.,Allard ST, Bingman CA, Johnson KA, Wesenberg GE, Bitto E, Jeon WB, Phillips GN Jr Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jul 1;61(Pt, 7):647-50. Epub 2005 Jun 30. PMID:16511118<ref>PMID:16511118</ref>
1VK5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VK5 OCA].


==Reference==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
Structure at 1.6 A resolution of the protein from gene locus At3g22680 from Arabidopsis thaliana., Allard ST, Bingman CA, Johnson KA, Wesenberg GE, Bitto E, Jeon WB, Phillips GN Jr, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jul 1;61(Pt, 7):647-50. Epub 2005 Jun 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16511118 16511118]
</div>
<div class="pdbe-citations 1vk5" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Allard, S T.M.]]
[[Category: Allard STM]]
[[Category: Bingman, C A.]]
[[Category: Bingman CA]]
[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
[[Category: Johnson KA]]
[[Category: Johnson, K A.]]
[[Category: Phillips Jr GN]]
[[Category: Jr., G N.Phillips.]]
[[Category: Smith DW]]
[[Category: Smith, D W.]]
[[Category: Wesenberg GE]]
[[Category: Wesenberg, G E.]]
[[Category: center for eukaryotic structural genomic]]
[[Category: cesg]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
[[Category: unknown function]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:09:52 2008''
Retrieved from "https://proteopedia.org/1vk5"