2iu5: Difference between revisions

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==DIHYDROXYACETONE KINASE OPERON ACTIVATOR DHAS==
 
<StructureSection load='2iu5' size='340' side='right' caption='[[2iu5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
==Dihydroxyacetone kinase operon activator DhaS==
<StructureSection load='2iu5' size='340' side='right'caption='[[2iu5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2iu5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lacla Lacla]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IU5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IU5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2iu5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis_subsp._lactis_Il1403 Lactococcus lactis subsp. lactis Il1403]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IU5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IU5 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iu5 OCA], [http://pdbe.org/2iu5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iu5 RCSB], [http://www.ebi.ac.uk/pdbsum/2iu5 PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iu5 OCA], [https://pdbe.org/2iu5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iu5 RCSB], [https://www.ebi.ac.uk/pdbsum/2iu5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iu5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DHAS_LACLA DHAS_LACLA]] In complex with DhaQ, upon activation by dihydroxyacetone, activates transcription of the dhaKLM operon. Binds the inverted repeat sequence 5'-GGACACATN(6)ATTTGTCC-3' located upstream of and partially overlapping with the -35 promoter sequence of the dhaKLM operon promoter.  
[https://www.uniprot.org/uniprot/DHAS_LACLA DHAS_LACLA] In complex with DhaQ, upon activation by dihydroxyacetone, activates transcription of the dhaKLM operon. Binds the inverted repeat sequence 5'-GGACACATN(6)ATTTGTCC-3' located upstream of and partially overlapping with the -35 promoter sequence of the dhaKLM operon promoter.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/2iu5_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/2iu5_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iu5 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lacla]]
[[Category: Lactococcus lactis subsp. lactis Il1403]]
[[Category: Baumann, U]]
[[Category: Large Structures]]
[[Category: Christen, S]]
[[Category: Baumann U]]
[[Category: Erni, B]]
[[Category: Christen S]]
[[Category: Srinivas, A]]
[[Category: Erni B]]
[[Category: Activator]]
[[Category: Srinivas A]]
[[Category: Synthase]]
[[Category: Tetr family]]
[[Category: Transcription]]
Retrieved from "https://proteopedia.org/2iu5"