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[[Image:1z9d.gif|left|200px]]


{{Structure
==Crystal structure of a putative uridylate kinase (UMP-kinase) from Streptococcus pyogenes==
|PDB= 1z9d |SIZE=350|CAPTION= <scene name='initialview01'>1z9d</scene>, resolution 2.80&Aring;
<StructureSection load='1z9d' size='340' side='right'caption='[[1z9d]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
<table><tr><td colspan='2'>[[1z9d]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z9D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z9D FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
|GENE= pyrH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1314 Streptococcus pyogenes])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04254 AAK_UMPK-PyrH-Ec]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z9d OCA], [https://pdbe.org/1z9d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z9d RCSB], [https://www.ebi.ac.uk/pdbsum/1z9d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z9d ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1z9d TOPSAN]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z9d OCA], [http://www.ebi.ac.uk/pdbsum/1z9d PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1z9d RCSB]</span>
</table>
}}
== Function ==
[https://www.uniprot.org/uniprot/PYRH_STRP1 PYRH_STRP1] Catalyzes the reversible phosphorylation of UMP to UDP (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z9/1z9d_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z9d ConSurf].
<div style="clear:both"></div>


'''Crystal structure of a putative uridylate kinase (UMP-kinase) from Streptococcus pyogenes'''
==See Also==
 
*[[Uridylate kinase|Uridylate kinase]]
 
__TOC__
==About this Structure==
</StructureSection>
1Z9D is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z9D OCA].
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Streptococcus pyogenes]]
[[Category: Streptococcus pyogenes]]
[[Category: Burley, S K.]]
[[Category: Burley SK]]
[[Category: Kniewel, R.]]
[[Category: Kniewel R]]
[[Category: Lee, K.]]
[[Category: Lee K]]
[[Category: Lima, C D.]]
[[Category: Lima CD]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Rajashankar KR]]
[[Category: Rajashankar, K R.]]
[[Category: new york structural genomix research consortium]]
[[Category: nysgxrc]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: putative uridylate kinase]]
[[Category: pyrh]]
[[Category: structural genomic]]
[[Category: t1668]]
[[Category: ump-kinase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:17:44 2008''