1vaq: Difference between revisions

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==Crystal structure of the Mg2+-(chromomycin A3)2-d(TTGGCCAA)2 complex reveals GGCC binding specificity of the drug dimer chelated by metal ion==
==Crystal structure of the Mg2+-(chromomycin A3)2-d(TTGGCCAA)2 complex reveals GGCC binding specificity of the drug dimer chelated by metal ion==
<StructureSection load='1vaq' size='340' side='right' caption='[[1vaq]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1vaq' size='340' side='right'caption='[[1vaq]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1vaq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VAQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VAQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1vaq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VAQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VAQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CPH:(1S)-5-DEOXY-1-O-METHYL-1-C-[(2R,3S)-3,5,7,10-TETRAHYDROXY-6-METHYL-4-OXO-1,2,3,4-TETRAHYDROANTHRACEN-2-YL]-D-XYLULOSE'>CPH</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=1GL:4-O-METHYL-2,6-DIDEOXY-ALPHA-D-GALACTO-HEXOPYRANOSE'>1GL</scene>, <scene name='pdbligand=ARI:[O4]-ACETOXY-2,3-DIDEOXYFUCOSE'>ARI</scene>, <scene name='pdbligand=CDR:2,3-DIDEOXYFUCOSE'>CDR</scene>, <scene name='pdbligand=ERI:4-O-ACETYL-2,6-DIDEOXY-3-C-METHYL-BETA-L-ARABINO-HEXOPYRANOSE'>ERI</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vaq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vaq OCA], [http://pdbe.org/1vaq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vaq RCSB], [http://www.ebi.ac.uk/pdbsum/1vaq PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1GL:4-O-METHYL-2,6-DIDEOXY-ALPHA-D-GALACTO-HEXOPYRANOSE'>1GL</scene>, <scene name='pdbligand=ARI:[O4]-ACETOXY-2,3-DIDEOXYFUCOSE'>ARI</scene>, <scene name='pdbligand=CDR:2,3-DIDEOXYFUCOSE'>CDR</scene>, <scene name='pdbligand=CPH:(1S)-5-DEOXY-1-O-METHYL-1-C-[(2R,3S)-3,5,7,10-TETRAHYDROXY-6-METHYL-4-OXO-1,2,3,4-TETRAHYDROANTHRACEN-2-YL]-D-XYLULOSE'>CPH</scene>, <scene name='pdbligand=ERI:4-O-ACETYL-2,6-DIDEOXY-3-C-METHYL-BETA-L-ARABINO-HEXOPYRANOSE'>ERI</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vaq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vaq OCA], [https://pdbe.org/1vaq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vaq RCSB], [https://www.ebi.ac.uk/pdbsum/1vaq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vaq ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Gao, Y G]]
[[Category: Large Structures]]
[[Category: Hou, M H]]
[[Category: Synthetic construct]]
[[Category: Robinson, H]]
[[Category: Gao YG]]
[[Category: Wang, A H.J]]
[[Category: Hou MH]]
[[Category: Cd spectra]]
[[Category: Robinson H]]
[[Category: Chromomycin a3]]
[[Category: Wang AH-J]]
[[Category: Dna]]
[[Category: Dna duplex]]
[[Category: Dna kink]]
[[Category: Ggcc site]]
[[Category: Mad]]
Retrieved from "https://proteopedia.org/1vaq"