2r75: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Aquifex aeolicus FtsZ with 8-morpholino-GTP==
==Aquifex aeolicus FtsZ with 8-morpholino-GTP==
<StructureSection load='2r75' size='340' side='right' caption='[[2r75]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='2r75' size='340' side='right'caption='[[2r75]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2r75]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R75 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R75 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2r75]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R75 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R75 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=01G:8-MORPHOLIN-4-YLGUANOSINE+5-(TETRAHYDROGEN+TRIPHOSPHATE)'>01G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.402&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2r6r|2r6r]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=01G:8-MORPHOLIN-4-YLGUANOSINE+5-(TETRAHYDROGEN+TRIPHOSPHATE)'>01G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ftsZ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 "Aquifex aeolicus" Huber and Stetter 2001])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r75 OCA], [https://pdbe.org/2r75 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r75 RCSB], [https://www.ebi.ac.uk/pdbsum/2r75 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r75 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r75 OCA], [http://pdbe.org/2r75 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2r75 RCSB], [http://www.ebi.ac.uk/pdbsum/2r75 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FTSZ_AQUAE FTSZ_AQUAE]] Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity).  
[https://www.uniprot.org/uniprot/FTSZ_AQUAE FTSZ_AQUAE] Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r7/2r75_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r7/2r75_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r75 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 31: Line 31:


==See Also==
==See Also==
*[[Cell division protein Ftsz|Cell division protein Ftsz]]
*[[Cell division protein 3D structures|Cell division protein 3D structures]]
*[[Tubulin|Tubulin]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aquifex aeolicus huber and stetter 2001]]
[[Category: Aquifex aeolicus]]
[[Category: Andreu, J M]]
[[Category: Large Structures]]
[[Category: Blaauwen, T den]]
[[Category: Andreu JM]]
[[Category: Hartog, A F]]
[[Category: Hartog AF]]
[[Category: Juhem, A]]
[[Category: Juhem A]]
[[Category: Koomen, G J]]
[[Category: Koomen GJ]]
[[Category: Lappchen, T]]
[[Category: Lappchen T]]
[[Category: Lowe, J]]
[[Category: Lowe J]]
[[Category: Pinas, V A]]
[[Category: Pinas VA]]
[[Category: Popov, A V]]
[[Category: Popov AV]]
[[Category: Schaffner-Barbero, C]]
[[Category: Schaffner-Barbero C]]
[[Category: Trambaiolo, D]]
[[Category: Trambaiolo D]]
[[Category: Cell cycle]]
[[Category: Den Blaauwen T]]
[[Category: Gtpase]]
[[Category: Inhibitor]]
[[Category: Tubulin-like]]