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==Crystal structure of Tk-RNase HII(1-204)-C==
==Crystal structure of Tk-RNase HII(1-204)-C==
<StructureSection load='2dff' size='340' side='right' caption='[[2dff]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='2dff' size='340' side='right'caption='[[2dff]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2dff]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_kodakaraensis_(strain_kod1) Pyrococcus kodakaraensis (strain kod1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DFF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2dff]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_kodakarensis_KOD1 Thermococcus kodakarensis KOD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DFF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DFF FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1io2|1io2]], [[2dfe|2dfe]], [[2dfg|2dfg]], [[2dfh|2dfh]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dff OCA], [https://pdbe.org/2dff PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dff RCSB], [https://www.ebi.ac.uk/pdbsum/2dff PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dff ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dff OCA], [http://pdbe.org/2dff PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dff RCSB], [http://www.ebi.ac.uk/pdbsum/2dff PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RNH2_THEKO RNH2_THEKO]] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.  
[https://www.uniprot.org/uniprot/RNH2_THEKO RNH2_THEKO] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/2dff_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/2dff_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dff ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
*[[Ribonuclease|Ribonuclease]]
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
*[[Temp|Temp]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ribonuclease H]]
[[Category: Large Structures]]
[[Category: Chon, H]]
[[Category: Thermococcus kodakarensis KOD1]]
[[Category: Kanaya, S]]
[[Category: Chon H]]
[[Category: Katagiri, Y]]
[[Category: Kanaya S]]
[[Category: Koga, Y]]
[[Category: Katagiri Y]]
[[Category: Matsumura, H]]
[[Category: Koga Y]]
[[Category: Takano, K]]
[[Category: Matsumura H]]
[[Category: Chameleon sequence]]
[[Category: Takano K]]
[[Category: Fusion protein]]
[[Category: Hydrolase]]
[[Category: Ribonuclease hii]]
[[Category: Thermococcus kodakaraensis]]

Latest revision as of 08:26, 25 October 2023

Crystal structure of Tk-RNase HII(1-204)-C

2dff, resolution 2.70Å

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