1oy5: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Crystal structure of tRNA (m1G37) methyltransferase from Aquifex aeolicus==
==Crystal structure of tRNA (m1G37) methyltransferase from Aquifex aeolicus==
<StructureSection load='1oy5' size='340' side='right' caption='[[1oy5]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='1oy5' size='340' side='right'caption='[[1oy5]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1oy5]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OY5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OY5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1oy5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OY5 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRMD OR AQ_1489 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 "Aquifex aeolicus" Huber and Stetter 2001])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.221 and 2.1.1.228 2.1.1.221 and 2.1.1.228] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oy5 OCA], [https://pdbe.org/1oy5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oy5 RCSB], [https://www.ebi.ac.uk/pdbsum/1oy5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oy5 ProSAT], [https://www.topsan.org/Proteins/BSGC/1oy5 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oy5 OCA], [http://pdbe.org/1oy5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1oy5 RCSB], [http://www.ebi.ac.uk/pdbsum/1oy5 PDBsum], [http://www.topsan.org/Proteins/BSGC/1oy5 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TRMD_AQUAE TRMD_AQUAE]] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]  
[https://www.uniprot.org/uniprot/TRMD_AQUAE TRMD_AQUAE] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oy/1oy5_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oy/1oy5_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oy5 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[TRNA methyltransferase|TRNA methyltransferase]]
*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aquifex aeolicus huber and stetter 2001]]
[[Category: Aquifex aeolicus]]
[[Category: Transferase]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Kim R]]
[[Category: Kim, R]]
[[Category: Kim SH]]
[[Category: Kim, S H]]
[[Category: Liu J]]
[[Category: Liu, J]]
[[Category: Shin DH]]
[[Category: Shin, D H]]
[[Category: Wang W]]
[[Category: Wang, W]]
[[Category: Yokota H]]
[[Category: Yokota, H]]
[[Category: Bsgc structure funded by nih]]
[[Category: PSI, Protein structure initiative]]
[[Category: Trmd]]

Latest revision as of 07:10, 30 October 2024

Crystal structure of tRNA (m1G37) methyltransferase from Aquifex aeolicus

1oy5, resolution 2.60Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA