5dst: Difference between revisions
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New page: '''Unreleased structure''' The entry 5dst is ON HOLD Authors: Toma-Fukai, S., Shimizu, T. Description: Crystal structure of human PRMT8 in complex with SAH [[Category: Unreleased Struc... |
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==Crystal structure of human PRMT8 in complex with SAH== | |||
<StructureSection load='5dst' size='340' side='right'caption='[[5dst]], [[Resolution|resolution]] 2.96Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5dst]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DST FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.963Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dst OCA], [https://pdbe.org/5dst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dst RCSB], [https://www.ebi.ac.uk/pdbsum/5dst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dst ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ANM8_HUMAN ANM8_HUMAN] Membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA). Able to mono- and dimethylate EWS protein; however its precise role toward EWS remains unclear as it still interacts with fully methylated EWS.<ref>PMID:16051612</ref> <ref>PMID:17925405</ref> <ref>PMID:18320585</ref> | |||
==See Also== | |||
*[[Histone methyltransferase 3D structures|Histone methyltransferase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Shimizu T]] | |||
[[Category: Toma-Fukai S]] | |||
Latest revision as of 09:10, 20 March 2024
Crystal structure of human PRMT8 in complex with SAH
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