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==Structures of the yeast dynamin-like GTPase Sey1p in complex with GDP==
==Structures of the yeast dynamin-like GTPase Sey1p in complex with GDP==
<StructureSection load='5ca8' size='340' side='right' caption='[[5ca8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='5ca8' size='340' side='right'caption='[[5ca8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ca8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CA8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ca8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CA8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ca9|5ca9]], [[5cb2|5cb2]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dynamin_GTPase Dynamin GTPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.5.5 3.6.5.5] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ca8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ca8 OCA], [https://pdbe.org/5ca8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ca8 RCSB], [https://www.ebi.ac.uk/pdbsum/5ca8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ca8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ca8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ca8 OCA], [http://pdbe.org/5ca8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ca8 RCSB], [http://www.ebi.ac.uk/pdbsum/5ca8 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SEY1_CANAL SEY1_CANAL]] Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization (By similarity). Required for virulence and resistance to cycloheximide.[HAMAP-Rule:MF_03109]<ref>PMID:12076781</ref>
[https://www.uniprot.org/uniprot/SEY1_CANAL SEY1_CANAL] Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization (By similarity). Required for virulence and resistance to cycloheximide.[HAMAP-Rule:MF_03109]<ref>PMID:12076781</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Dynamin GTPase]]
[[Category: Candida albicans SC5314]]
[[Category: Yan, L]]
[[Category: Large Structures]]
[[Category: Dynamin]]
[[Category: Yan L]]
[[Category: Er]]
[[Category: Homo-fusion]]
[[Category: Hydrolase]]
Retrieved from "https://proteopedia.org/5ca8"