5e26: Difference between revisions
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The entry | ==Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate== | ||
<StructureSection load='5e26' size='340' side='right'caption='[[5e26]], [[Resolution|resolution]] 2.14Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5e26]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E26 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E26 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PAU:PANTOTHENOIC+ACID'>PAU</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e26 OCA], [https://pdbe.org/5e26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e26 RCSB], [https://www.ebi.ac.uk/pdbsum/5e26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e26 ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/PANK2_HUMAN PANK2_HUMAN] Atypical pantothenate kinase-associated neurodegeneration;Classic pantothenate kinase-associated neurodegeneration. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PANK2_HUMAN PANK2_HUMAN] May be the master regulator of the CoA biosynthesis. | |||
==See Also== | |||
*[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: BROWN PJ]] | ||
[[Category: | [[Category: Bountra C]] | ||
[[Category: | [[Category: CHENG C]] | ||
[[Category: | [[Category: DONG A]] | ||
[[Category: | [[Category: Edwards AM]] | ||
[[Category: | [[Category: HONG BS]] | ||
[[Category: | [[Category: HUTCHINSON A]] | ||
[[Category: | [[Category: LOPPNAU P]] | ||
[[Category: | [[Category: RAVICHANDRAN M]] | ||
[[Category: | [[Category: SEITOVA A]] | ||
[[Category: TEMPEL W]] | |||
Latest revision as of 06:10, 5 July 2023
Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate
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